Transplantation for myocarditis: A controversy revisited

Edward D. Moloney, Jim J. Egan, Peter Kelly, Alfred E. Wood, Leslie T. Cooper

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Myocarditis is a major cause of end-stage heart failure and is responsible for up to 10% of cases of idiopathic dilated cardiomyopathy (IDC). Worldwide, approximately 45% of all heart transplants are performed for IDC and up to 8% for myocarditis. Early reports suggested that survival after transplantation for myocarditis was poor and patients had an increased risk of rejection. More recently, larger case series suggest that overall survival after transplantation for myocarditis is similar to survival after transplantation for other causes. However, certain disorders, including cardiac sarcoidosis and giant cell myocarditis (GCM), require heightened surveillance for post-transplantation disease recurrence. We present the case of a 42-year-old man with recurrence of GCM 8 years after transplantation and review the literature on the role of cardiac transplantation for patients with myocarditis.

Original languageEnglish (US)
Pages (from-to)1103-1110
Number of pages8
JournalJournal of Heart and Lung Transplantation
Volume24
Issue number8
DOIs
StatePublished - Aug 2005

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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