Abstract
Analysis of G-banded prometaphase chromosomes from three XX males revealed extra bands on the distal end of one X short arm. These bands were similar both in size and staining properties to the distal Y short arm of their fathers (in the two cases examined) and also to other chromosomally normal males. The extra material on the abnormal X chromosomes was not C-or G-11 positive in the two cases examined, suggesting that the proximal Y long arm was not present. Previous karyotype-phenotype correlations with structurally altered Y chromosomes provided evidence for localization of male determinants on the Y short arm. The present findings in XX males provide support for more precise localization, to bands p11.2→pter of Y short arm.
Original language | English (US) |
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Pages (from-to) | 271-276 |
Number of pages | 6 |
Journal | Human genetics |
Volume | 62 |
Issue number | 3 |
DOIs | |
State | Published - Dec 1982 |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)