Translational molecular self-diffusion in magnetic resonance imaging: II. Measurement of the self-diffusion coefficient

George E. Wesbey, Michael E. Moseley, Richard L. Ehman

Research output: Contribution to journalArticle

107 Scopus citations

Abstract

By varying slice-selective gradients in successive data acquisitions, the first in vitro measurements of molecular self-diffusion coefficients were performed in a magnetic resonance imager at 0.35 Tesla. Reasonably accurate measurements were found by the MRI method in comparison with 2.3 T NMR spectrometer measurements on the same samples, and in comparison to reported literature values. Thus, in addition to T1, T2, mobile proton density, flow velocity, magnetic susceptibility, and chemical shift, molecular self- diffusion coefficients are now added to the list of biophysical parameters measurable by magnetic resonance imaging in the noninvasive characterization of biological systems.

Original languageEnglish (US)
Pages (from-to)491-498
Number of pages8
JournalInvestigative radiology
Volume19
Issue number6
DOIs
StatePublished - Jan 1 1984

Keywords

  • Magnetic resonance imaging
  • Self-diffusion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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