TY - JOUR
T1 - Translational molecular self-diffusion in magnetic resonance imaging
T2 - II. Measurement of the self-diffusion coefficient
AU - Wesbey, George E.
AU - Moseley, Michael E.
AU - Ehman, Richard L.
PY - 1984
Y1 - 1984
N2 - By varying slice-selective gradients in successive data acquisitions, the first in vitro measurements of molecular self-diffusion coefficients were performed in a magnetic resonance imager at 0.35 Tesla. Reasonably accurate measurements were found by the MRI method in comparison with 2.3 T NMR spectrometer measurements on the same samples, and in comparison to reported literature values. Thus, in addition to T1, T2, mobile proton density, flow velocity, magnetic susceptibility, and chemical shift, molecular self- diffusion coefficients are now added to the list of biophysical parameters measurable by magnetic resonance imaging in the noninvasive characterization of biological systems.
AB - By varying slice-selective gradients in successive data acquisitions, the first in vitro measurements of molecular self-diffusion coefficients were performed in a magnetic resonance imager at 0.35 Tesla. Reasonably accurate measurements were found by the MRI method in comparison with 2.3 T NMR spectrometer measurements on the same samples, and in comparison to reported literature values. Thus, in addition to T1, T2, mobile proton density, flow velocity, magnetic susceptibility, and chemical shift, molecular self- diffusion coefficients are now added to the list of biophysical parameters measurable by magnetic resonance imaging in the noninvasive characterization of biological systems.
KW - Magnetic resonance imaging
KW - Self-diffusion
UR - http://www.scopus.com/inward/record.url?scp=0021690998&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021690998&partnerID=8YFLogxK
U2 - 10.1097/00004424-198411000-00005
DO - 10.1097/00004424-198411000-00005
M3 - Article
C2 - 6511256
AN - SCOPUS:0021690998
SN - 0020-9996
VL - 19
SP - 491
EP - 498
JO - Investigative radiology
JF - Investigative radiology
IS - 6
ER -