Transitions in symptom cluster subgroups among men undergoing prostate cancer radiation therapy

Shannon Ruff Dirksen, Michael J. Belyea, William Wong, Dana R. Epstein

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Prostate cancer is a common type of cancer worldwide and in the United States. However, little information has been reported on the symptoms of men over time who receive radiation therapy. Objective: The objectives of this study were to identify subgroups of men at pre- and post-radiation therapy on general and treatment-related symptoms and to determine transitions in subgroup membership over time. Methods: Men (n = 84) receiving radiation therapy completed questionnaires on fatigue, insomnia, pain, depression, anxiety, and sexual, urinary, and bowel problems at pretreatment and posttreatment. Latent class analysis identified subgroups. One-way analyses of variance determined subgroups differed on symptoms, participant characteristics, and quality of life. Latent transition analysis examined subgroup transitions over time. Results: At pretreatment, 4 subgroups were identified: resilient group, with little to no symptom reporting; adjusted group, with moderately high treatment-related symptoms, low insomnia, depression, and anxiety; distressed group, consistently high on most symptoms; and emerging group, with moderately high fatigue, depression, and anxiety with few treatment-related symptoms. At posttreatment, similar results were seen in groups to those at pretreatment: resilient, adjusted. and distressed groups with an impacted group having high pain, insomnia, depression, and urinary and bowel symptoms. Quality of life and participant characteristics further distinguished groups at pretreatment and posttreatment. Income level predicted a transition in group membership. Conclusions: Men can be classified into distinctly different subgroups over time. Implications for Practice: Assessment and intervention with men in subgroups such as distressed and emerging before and during treatment may lessen potential for remaining distressed or moving into impacted group where symptom severity is high at posttreatment. Interventions to reduce multiple symptoms are vitally needed.

Original languageEnglish (US)
Pages (from-to)3-11
Number of pages9
JournalCancer Nursing
Volume39
Issue number1
DOIs
StatePublished - Jan 1 2016

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Prostatic Neoplasms
Radiotherapy
Sleep Initiation and Maintenance Disorders
Depression
Anxiety
Fatigue
Quality of Life
Pain
Therapeutics
Analysis of Variance
Radiation
Neoplasms

Keywords

  • Prostate cancer
  • Quality of life
  • Radiation therapy
  • Symptom clusters

ASJC Scopus subject areas

  • Oncology
  • Oncology(nursing)

Cite this

Transitions in symptom cluster subgroups among men undergoing prostate cancer radiation therapy. / Dirksen, Shannon Ruff; Belyea, Michael J.; Wong, William; Epstein, Dana R.

In: Cancer Nursing, Vol. 39, No. 1, 01.01.2016, p. 3-11.

Research output: Contribution to journalArticle

Dirksen, Shannon Ruff ; Belyea, Michael J. ; Wong, William ; Epstein, Dana R. / Transitions in symptom cluster subgroups among men undergoing prostate cancer radiation therapy. In: Cancer Nursing. 2016 ; Vol. 39, No. 1. pp. 3-11.
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