Transition from childhood to adulthood in coeliac disease: The Prague consensus report

Jonas F. Ludvigsson, Lars Agreus, Carolina Ciacci, Sheila E. Crowe, Marilyn G. Geller, Peter H R Green, Ivor Hill, A. Pali Hungin, Sibylle Koletzko, Tunde Koltai, Knut E A Lundin, M. Luisa Mearin, Joseph A Murray, Norelle Reilly, Marjorie M. Walker, David S. Sanders, Raanan Shamir, Riccardo Troncone, Steffen Husby

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The process of transition from childhood to adulthood is characterised by physical, mental and psychosocial development. Data on the transition and transfer of care in adolescents/young adults with coeliac disease (CD) are scarce. In this paper, 17 physicians from 10 countries (Sweden, Italy, the USA, Germany, Norway, the Netherlands, Australia, Britain, Israel and Denmark) and two representatives from patient organisations (Association of European Coeliac Societies and the US Celiac Disease Foundation) examined the literature on transition from childhood to adulthood in CD. Medline (Ovid) and EMBASE were searched between 1900 and September 2015. Evidence in retrieved reports was evaluated using the Grading of Recommendation Assessment, Development and Evaluation method. The current consensus report aims to help healthcare personnel manage CD in the adolescent and young adult and provide optimal care and transition into adult healthcare for patients with this disease. In adolescence, patients with CD should gradually assume exclusive responsibility for their care, although parental support is still important. Dietary adherence and consequences of non-Adherence should be discussed during transition. In most adolescents and young adults, routine small intestinal biopsy is not needed to reconfirm a childhood diagnosis of CD based on European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) or North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) criteria, but a biopsy may be considered where paediatric diagnostic criteria have not been fulfilled, such as, in a patient without biopsy at diagnosis, additional serology (endomysium antibody) has not been performed to confirm 10-fold positivity of tissue transglutaminase antibodies or when a no biopsy strategy has been adopted in an asymptomatic child.

Original languageEnglish (US)
Pages (from-to)1242-1251
Number of pages10
JournalGut
Volume65
Issue number8
DOIs
StatePublished - Aug 1 2016

Fingerprint

Celiac Disease
Biopsy
Patient Transfer
Young Adult
Gastroenterology
Pediatrics
Delivery of Health Care
Patient Advocacy
Antibodies
Israel
Serology
Denmark
Norway
Sweden
Netherlands
Abdomen
Italy
Germany
Organizations
Physicians

Keywords

  • CELIAC DISEASE
  • COELIAC DISEASE
  • GLUTEN

ASJC Scopus subject areas

  • Medicine(all)
  • Gastroenterology

Cite this

Ludvigsson, J. F., Agreus, L., Ciacci, C., Crowe, S. E., Geller, M. G., Green, P. H. R., ... Husby, S. (2016). Transition from childhood to adulthood in coeliac disease: The Prague consensus report. Gut, 65(8), 1242-1251. https://doi.org/10.1136/gutjnl-2016-311574

Transition from childhood to adulthood in coeliac disease : The Prague consensus report. / Ludvigsson, Jonas F.; Agreus, Lars; Ciacci, Carolina; Crowe, Sheila E.; Geller, Marilyn G.; Green, Peter H R; Hill, Ivor; Hungin, A. Pali; Koletzko, Sibylle; Koltai, Tunde; Lundin, Knut E A; Mearin, M. Luisa; Murray, Joseph A; Reilly, Norelle; Walker, Marjorie M.; Sanders, David S.; Shamir, Raanan; Troncone, Riccardo; Husby, Steffen.

In: Gut, Vol. 65, No. 8, 01.08.2016, p. 1242-1251.

Research output: Contribution to journalArticle

Ludvigsson, JF, Agreus, L, Ciacci, C, Crowe, SE, Geller, MG, Green, PHR, Hill, I, Hungin, AP, Koletzko, S, Koltai, T, Lundin, KEA, Mearin, ML, Murray, JA, Reilly, N, Walker, MM, Sanders, DS, Shamir, R, Troncone, R & Husby, S 2016, 'Transition from childhood to adulthood in coeliac disease: The Prague consensus report', Gut, vol. 65, no. 8, pp. 1242-1251. https://doi.org/10.1136/gutjnl-2016-311574
Ludvigsson JF, Agreus L, Ciacci C, Crowe SE, Geller MG, Green PHR et al. Transition from childhood to adulthood in coeliac disease: The Prague consensus report. Gut. 2016 Aug 1;65(8):1242-1251. https://doi.org/10.1136/gutjnl-2016-311574
Ludvigsson, Jonas F. ; Agreus, Lars ; Ciacci, Carolina ; Crowe, Sheila E. ; Geller, Marilyn G. ; Green, Peter H R ; Hill, Ivor ; Hungin, A. Pali ; Koletzko, Sibylle ; Koltai, Tunde ; Lundin, Knut E A ; Mearin, M. Luisa ; Murray, Joseph A ; Reilly, Norelle ; Walker, Marjorie M. ; Sanders, David S. ; Shamir, Raanan ; Troncone, Riccardo ; Husby, Steffen. / Transition from childhood to adulthood in coeliac disease : The Prague consensus report. In: Gut. 2016 ; Vol. 65, No. 8. pp. 1242-1251.
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