Abstract
Transient neuroimaging abnormalities associated with seizure activity have received little attention in the literature. The authors report a focal magnetic resonance (MR) imaging abnormality of the corpus callosum in a patient following a secondary generalized seizure. A 27-year-old right-handed man presented with a history of medically refractory partial seizures since the age of 1 year. The results of an MR imaging study obtained 4 months prior to the patient undergoing video-electroencephalography monitoring were unremarkable. After the patient discontinued all antiepileptic medications, a secondary generalized seizure of right temporal origin was recorded. Five days later, repeated MR imaging revealed a nonenhancing 14 × 11-mm ovoid hyperintense lesion in the splenium of corpus callosum. The patient was asymptomatic, and his neurological and neurocognitive examinations remained unremarkable. Follow-up MR imaging 5 weeks and 1 year later demonstrated near-complete resolution of the lesion. Benign and transient abnormalities in the splenium can occur as a periictal phenomenon. A high index of suspicion and follow-up imaging may prevent further unwarranted intervention.
Original language | English (US) |
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Pages (from-to) | 714-717 |
Number of pages | 4 |
Journal | Journal of neurosurgery |
Volume | 97 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2002 |
Keywords
- Corpus callosum
- Epilepsy
- Magnetic resonance imaging
- Seizure
- Splenium
ASJC Scopus subject areas
- Surgery
- Clinical Neurology