Transient postictal magnetic resonance imaging abnormality of the corpus callosum in a patient with epilepsy: Case report and review of the literature

Aaron A. Cohen-Gadol, Jeffrey W. Britton, Clifford R Jr. Jack, Jonathan A. Friedman, W. Richard Marsh

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Transient neuroimaging abnormalities associated with seizure activity have received little attention in the literature. The authors report a focal magnetic resonance (MR) imaging abnormality of the corpus callosum in a patient following a secondary generalized seizure. A 27-year-old right-handed man presented with a history of medically refractory partial seizures since the age of 1 year. The results of an MR imaging study obtained 4 months prior to the patient undergoing video-electroencephalography monitoring were unremarkable. After the patient discontinued all antiepileptic medications, a secondary generalized seizure of right temporal origin was recorded. Five days later, repeated MR imaging revealed a nonenhancing 14 × 11-mm ovoid hyperintense lesion in the splenium of corpus callosum. The patient was asymptomatic, and his neurological and neurocognitive examinations remained unremarkable. Follow-up MR imaging 5 weeks and 1 year later demonstrated near-complete resolution of the lesion. Benign and transient abnormalities in the splenium can occur as a periictal phenomenon. A high index of suspicion and follow-up imaging may prevent further unwarranted intervention.

Original languageEnglish (US)
Pages (from-to)714-717
Number of pages4
JournalJournal of Neurosurgery
Volume97
Issue number3
StatePublished - Sep 2002

Fingerprint

Corpus Callosum
Epilepsy
Seizures
Magnetic Resonance Imaging
Neurologic Examination
Neuroimaging
Anticonvulsants
Electroencephalography

Keywords

  • Corpus callosum
  • Epilepsy
  • Magnetic resonance imaging
  • Seizure
  • Splenium

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Transient postictal magnetic resonance imaging abnormality of the corpus callosum in a patient with epilepsy : Case report and review of the literature. / Cohen-Gadol, Aaron A.; Britton, Jeffrey W.; Jack, Clifford R Jr.; Friedman, Jonathan A.; Marsh, W. Richard.

In: Journal of Neurosurgery, Vol. 97, No. 3, 09.2002, p. 714-717.

Research output: Contribution to journalArticle

Cohen-Gadol, Aaron A. ; Britton, Jeffrey W. ; Jack, Clifford R Jr. ; Friedman, Jonathan A. ; Marsh, W. Richard. / Transient postictal magnetic resonance imaging abnormality of the corpus callosum in a patient with epilepsy : Case report and review of the literature. In: Journal of Neurosurgery. 2002 ; Vol. 97, No. 3. pp. 714-717.
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