Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: A case report

Majd D. Jawad; Ronald S. Go; Rhett P. Ketterling; Kebede H. Begna; Kaaren K. Reichard; Min Shi

doi:10.1002/ccr3.506

Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: A case report

Majd D. Jawad, Ronald S. Go, Rhett P. Ketterling, Kebede H. Begna, Kaaren K. Reichard, Min Shi

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4 Scopus citations

Abstract

Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph-) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph- cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.

Original language	English (US)
Pages (from-to)	282-286
Number of pages	5
Journal	Clinical Case Reports
Volume	4
Issue number	3
DOIs	https://doi.org/10.1002/ccr3.506
State	Published - Mar 1 2016

Keywords

Chronic myelogenous leukemia
Monosomy 7

ASJC Scopus subject areas

General Medicine

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10.1002/ccr3.506

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title = "Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: A case report",

abstract = "Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph-) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph- cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.",

keywords = "Chronic myelogenous leukemia, Monosomy 7",

author = "Jawad, {Majd D.} and Go, {Ronald S.} and Ketterling, {Rhett P.} and Begna, {Kebede H.} and Reichard, {Kaaren K.} and Min Shi",

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AU - Ketterling, Rhett P.

AU - Begna, Kebede H.

AU - Reichard, Kaaren K.

AU - Shi, Min

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph-) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph- cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.

AB - Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph-) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph- cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.

KW - Chronic myelogenous leukemia

KW - Monosomy 7

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Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: A case report

Abstract

Keywords

ASJC Scopus subject areas

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