Transfemoral transcatheter aortic valve insertion-related intraoperative morbidity: Implications of the minimalist approach

Kevin L. Greason, Alberto Pochettino, Gurpreet S. Sandhu, Katherine S. King, David R. Holmes

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objectives Transfemoral transcatheter aortic valve insertion may be performed in a catheterization laboratory (ie, the minimalist approach). It seems reasonable when considering this approach to avoid it in patients at risk for intraoperative morbidity that would require surgical intervention. We hypothesized that it would be possible to associate baseline characteristics with such morbidity, which would help heart teams select patients for the minimalist approach. Methods We reviewed the records of 215 consecutive patients who underwent transfemoral transcatheter aortic valve insertion with a current commercially available device from November 2008 through July 2015. Demographic characteristics of the patients included a mean age of 78.9 ± 10.6 years, female sex in 73 patients (34.0%), and a mean Society of Thoracic Surgeons predicted risk of mortality of 8.7% ± 5.4%. Valve prostheses were balloon-expandable in 126 patients (58.6%) and self-expanding in 89 patients (41.4%). Results Significant intraoperative morbidity occurred in 22 patients (10.2%) and included major vascular injury in 12 patients (5.6%), hemodynamic compromise requiring cardiopulmonary bypass support in 4 patients (1.9%), cardiac tamponade requiring intervention in 3 patients (1.4%), ventricular valve embolization in 2 patients (0.9%), and inability to obtain percutaneous access requiring open vascular access in 1 patient (0.5%). Intraoperative morbidity was similarly distributed across all valve types (P =.556) and sheath sizes (P =.369). There were no baseline patient characteristics predictive of intraoperative morbidity. Conclusions Patient and valve characteristics are not predictive of significant intraoperative morbidity during transfemoral transcatheter aortic valve insertion. The finding has implications for patient selection for the minimalist approach.

Original languageEnglish (US)
Pages (from-to)1026-1029
Number of pages4
JournalJournal of Thoracic and Cardiovascular Surgery
Issue number4
StatePublished - Apr 1 2016


  • catheterization
  • complications
  • hybrid operating room
  • laboratory
  • minimalist
  • transapical
  • transcatheter aortic valve insertion
  • transcatheter aortic valve replacement
  • transfemoral

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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