Transdermal clonidine for ameliorating post-orchiectomy hot flashes

Charles Lawrence Loprinzi, R. M. Goldberg, J. R. O'Fallon, S. K. Quella, A. W. Miser, L. A. Mynderse, L. D. Brown, L. K. Tschetter, M. B. Wilwerding, A. M. Dose, J. E. Oesterling

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

To determine the efficacy of transdermal clonidine for alleviating post- orchiectomy hot flashes, a randomized, double-blind, crossover clinical trial was designed including 70 men with a history of prostate cancer who had undergone a medical or surgical orchiectomy and were suffering from hot flashes. The results of this study demonstrated that clonidine did not significantly decrease hot flash frequency or severity. Future research is necessary to find effective means of alleviating hot flashes in post- orchiectomy patients.

Original languageEnglish (US)
Pages (from-to)634-636
Number of pages3
JournalJournal of Urology
Volume151
Issue number3
StatePublished - 1994

Fingerprint

Hot Flashes
Orchiectomy
Clonidine
Cross-Over Studies
Prostatic Neoplasms
Clinical Trials

Keywords

  • clonidine
  • flushing
  • orchiectomy
  • prostatic neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Loprinzi, C. L., Goldberg, R. M., O'Fallon, J. R., Quella, S. K., Miser, A. W., Mynderse, L. A., ... Oesterling, J. E. (1994). Transdermal clonidine for ameliorating post-orchiectomy hot flashes. Journal of Urology, 151(3), 634-636.

Transdermal clonidine for ameliorating post-orchiectomy hot flashes. / Loprinzi, Charles Lawrence; Goldberg, R. M.; O'Fallon, J. R.; Quella, S. K.; Miser, A. W.; Mynderse, L. A.; Brown, L. D.; Tschetter, L. K.; Wilwerding, M. B.; Dose, A. M.; Oesterling, J. E.

In: Journal of Urology, Vol. 151, No. 3, 1994, p. 634-636.

Research output: Contribution to journalArticle

Loprinzi, CL, Goldberg, RM, O'Fallon, JR, Quella, SK, Miser, AW, Mynderse, LA, Brown, LD, Tschetter, LK, Wilwerding, MB, Dose, AM & Oesterling, JE 1994, 'Transdermal clonidine for ameliorating post-orchiectomy hot flashes', Journal of Urology, vol. 151, no. 3, pp. 634-636.
Loprinzi CL, Goldberg RM, O'Fallon JR, Quella SK, Miser AW, Mynderse LA et al. Transdermal clonidine for ameliorating post-orchiectomy hot flashes. Journal of Urology. 1994;151(3):634-636.
Loprinzi, Charles Lawrence ; Goldberg, R. M. ; O'Fallon, J. R. ; Quella, S. K. ; Miser, A. W. ; Mynderse, L. A. ; Brown, L. D. ; Tschetter, L. K. ; Wilwerding, M. B. ; Dose, A. M. ; Oesterling, J. E. / Transdermal clonidine for ameliorating post-orchiectomy hot flashes. In: Journal of Urology. 1994 ; Vol. 151, No. 3. pp. 634-636.
@article{6e53d16576ff4d00b51de54b1b558f48,
title = "Transdermal clonidine for ameliorating post-orchiectomy hot flashes",
abstract = "To determine the efficacy of transdermal clonidine for alleviating post- orchiectomy hot flashes, a randomized, double-blind, crossover clinical trial was designed including 70 men with a history of prostate cancer who had undergone a medical or surgical orchiectomy and were suffering from hot flashes. The results of this study demonstrated that clonidine did not significantly decrease hot flash frequency or severity. Future research is necessary to find effective means of alleviating hot flashes in post- orchiectomy patients.",
keywords = "clonidine, flushing, orchiectomy, prostatic neoplasms",
author = "Loprinzi, {Charles Lawrence} and Goldberg, {R. M.} and O'Fallon, {J. R.} and Quella, {S. K.} and Miser, {A. W.} and Mynderse, {L. A.} and Brown, {L. D.} and Tschetter, {L. K.} and Wilwerding, {M. B.} and Dose, {A. M.} and Oesterling, {J. E.}",
year = "1994",
language = "English (US)",
volume = "151",
pages = "634--636",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Transdermal clonidine for ameliorating post-orchiectomy hot flashes

AU - Loprinzi, Charles Lawrence

AU - Goldberg, R. M.

AU - O'Fallon, J. R.

AU - Quella, S. K.

AU - Miser, A. W.

AU - Mynderse, L. A.

AU - Brown, L. D.

AU - Tschetter, L. K.

AU - Wilwerding, M. B.

AU - Dose, A. M.

AU - Oesterling, J. E.

PY - 1994

Y1 - 1994

N2 - To determine the efficacy of transdermal clonidine for alleviating post- orchiectomy hot flashes, a randomized, double-blind, crossover clinical trial was designed including 70 men with a history of prostate cancer who had undergone a medical or surgical orchiectomy and were suffering from hot flashes. The results of this study demonstrated that clonidine did not significantly decrease hot flash frequency or severity. Future research is necessary to find effective means of alleviating hot flashes in post- orchiectomy patients.

AB - To determine the efficacy of transdermal clonidine for alleviating post- orchiectomy hot flashes, a randomized, double-blind, crossover clinical trial was designed including 70 men with a history of prostate cancer who had undergone a medical or surgical orchiectomy and were suffering from hot flashes. The results of this study demonstrated that clonidine did not significantly decrease hot flash frequency or severity. Future research is necessary to find effective means of alleviating hot flashes in post- orchiectomy patients.

KW - clonidine

KW - flushing

KW - orchiectomy

KW - prostatic neoplasms

UR - http://www.scopus.com/inward/record.url?scp=0027980008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027980008&partnerID=8YFLogxK

M3 - Article

C2 - 8308973

AN - SCOPUS:0027980008

VL - 151

SP - 634

EP - 636

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 3

ER -