Transcriptional control of gene expression in pancreatic cancer: From sequence-specific transcription factors to nuclear architecture

Volker Ellenrieder, Martin E. Fernandez-Zapico

Research output: Contribution to journalArticle

Abstract

Transcription plays a central role in the regulation of gene expression during neoplastic transformation in different tissues. Using this nuclear process as a common topic in this special issue of the Journal of Gastrointestinal Cancer we have covered with five review articles key aspects of gene transcription and its impact in pancreatic carcinogenesis. We are confident that the knowledge included in these review articles will help understand the contribution of this molecular event to the pathogenesis of this devastating disease and serve as foundation for the development of new therapeutic tools.

Original languageEnglish (US)
Pages (from-to)73-75
Number of pages3
JournalJournal of gastrointestinal cancer
Volume42
Issue number2
DOIs
StatePublished - Jun 1 2011

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Keywords

  • Chromatin
  • Gene expression
  • Nucleus
  • Pancreatic cancer
  • Transcription

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

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