TY - JOUR
T1 - Towards individualized medicine
T2 - Insights gained from genomic studies
AU - Kirmani, Salman
AU - Babovic-Vuksanovic, Dusica
PY - 2009
Y1 - 2009
N2 - Advances in the field of human genetics have made it possible to develop specific management and prevention strategies for rare genetic disorders, and tailor pharmacotherapeutic approaches to anticoagulation and certain cancers. The role that genetic variation plays in influencing the risk and outcome of the most common diseases are still unclear. Data from genomewide association studies is just beginning to answer these questions. We review the role of genome-wide association studies in the quest towards individualized medicine, and examine the promises and challenges that lie ahead.
AB - Advances in the field of human genetics have made it possible to develop specific management and prevention strategies for rare genetic disorders, and tailor pharmacotherapeutic approaches to anticoagulation and certain cancers. The role that genetic variation plays in influencing the risk and outcome of the most common diseases are still unclear. Data from genomewide association studies is just beginning to answer these questions. We review the role of genome-wide association studies in the quest towards individualized medicine, and examine the promises and challenges that lie ahead.
KW - Genome-wide association studies
KW - Single nucleotide polymorphism
KW - Spersonalized medicine
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U2 - 10.17305/bjbms.2009.2748
DO - 10.17305/bjbms.2009.2748
M3 - Article
C2 - 19912112
AN - SCOPUS:73949149250
SN - 1512-8601
VL - 9
SP - S11-S16
JO - Bosnian journal of basic medical sciences
JF - Bosnian journal of basic medical sciences
IS - SUPPL.
ER -