Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy.

Cristian A. Linte, Jon J. Camp, David R. Holmes III, Maryam E. Rettmann, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Despite extensive efforts to enhance catheter navigation, limited research has been done to visualize and monitor the tissue lesions created during ablation in the attempt to provide feedback for effective therapy. We propose a technique to visualize the temperature distribution and extent of induced tissue injury via an image-based model that uses physiological tissue parameters and relies on heat transfer principles to characterize lesion progression in near real time. The model was evaluated both numerically and experimentally using ex vivo bovine muscle samples while emulating a clinically relevant ablation protocol. Results show agreement to within 5 degreeC between the model-predicted and experimentally measured end-ablation tissue temperatures, as well as comparable predicted and observed lesion characteristics. The model yields temperature and lesion updates in near real-time, thus providing reasonably accurate and sufficiently fast monitoring for effective therapy.

Original languageEnglish (US)
Title of host publicationMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Pages9-17
Number of pages9
Volume16
EditionPt 1
StatePublished - 2013

Fingerprint

Temperature
Therapeutics
Catheters
Hot Temperature
Muscles
Wounds and Injuries
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Linte, C. A., Camp, J. J., Holmes III, D. R., Rettmann, M. E., & Robb, R. A. (2013). Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy. In Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention (Pt 1 ed., Vol. 16, pp. 9-17)

Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy. / Linte, Cristian A.; Camp, Jon J.; Holmes III, David R.; Rettmann, Maryam E.; Robb, Richard A.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Vol. 16 Pt 1. ed. 2013. p. 9-17.

Research output: Chapter in Book/Report/Conference proceedingChapter

Linte, CA, Camp, JJ, Holmes III, DR, Rettmann, ME & Robb, RA 2013, Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy. in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 1 edn, vol. 16, pp. 9-17.
Linte CA, Camp JJ, Holmes III DR, Rettmann ME, Robb RA. Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy. In Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 1 ed. Vol. 16. 2013. p. 9-17
Linte, Cristian A. ; Camp, Jon J. ; Holmes III, David R. ; Rettmann, Maryam E. ; Robb, Richard A. / Toward online modeling for lesion visualization and monitoring in cardiac ablation therapy. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Vol. 16 Pt 1. ed. 2013. pp. 9-17
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