Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model

Gerwin Schalk; Samuel Worrell; Filip Mivalt; Alexander Belsten; Inyong Kim; Jonathan M. Morris; Dora Hermes; Bryan T. Klassen; Nathan P. Staff; Steven Messina; Timothy Kaufmann; Jörn Rickert; Peter Brunner; Gregory A. Worrell; Kai J. Miller

doi:10.3389/fnins.2022.932782

Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model

Gerwin Schalk, Samuel Worrell, Filip Mivalt, Alexander Belsten, Inyong Kim, Jonathan M. Morris, Dora Hermes, Bryan T. Klassen, Nathan P. Staff, Steven Messina, Timothy Kaufmann, Jörn Rickert, Peter Brunner, Gregory A. Worrell, Kai J. Miller

Research output: Contribution to journal › Article › peer-review

Abstract

This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.

Original language	English (US)
Article number	932782
Journal	Frontiers in Neuroscience
Volume	16
DOIs	https://doi.org/10.3389/fnins.2022.932782
State	Published - Dec 19 2022

Keywords

adaptive
brain–computer interface
invasive
neuromodulation
neurotechnology

ASJC Scopus subject areas

General Neuroscience

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10.3389/fnins.2022.932782

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Schalk, G., Worrell, S., Mivalt, F., Belsten, A., Kim, I., Morris, J. M., Hermes, D., Klassen, B. T., Staff, N. P., Messina, S., Kaufmann, T., Rickert, J., Brunner, P., Worrell, G. A., & Miller, K. J. (2022). Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model. Frontiers in Neuroscience, 16, Article 932782. https://doi.org/10.3389/fnins.2022.932782

Schalk, G, Worrell, S, Mivalt, F, Belsten, A, Kim, I, Morris, JM, Hermes, D , Klassen, BT , Staff, NP, Messina, S, Kaufmann, T, Rickert, J, Brunner, P, Worrell, GA & Miller, KJ 2022, 'Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model', Frontiers in Neuroscience, vol. 16, 932782. https://doi.org/10.3389/fnins.2022.932782

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title = "Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model",

abstract = "This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.",

keywords = "adaptive, brain–computer interface, invasive, neuromodulation, neurotechnology",

author = "Gerwin Schalk and Samuel Worrell and Filip Mivalt and Alexander Belsten and Inyong Kim and Morris, {Jonathan M.} and Dora Hermes and Klassen, {Bryan T.} and Staff, {Nathan P.} and Steven Messina and Timothy Kaufmann and J{\"o}rn Rickert and Peter Brunner and Worrell, {Gregory A.} and Miller, {Kai J.}",

note = "Publisher Copyright: Copyright {\textcopyright} 2022 Schalk, Worrell, Mivalt, Belsten, Kim, Morris, Hermes, Klassen, Staff, Messina, Kaufmann, Rickert, Brunner, Worrell and Miller.",

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AU - Klassen, Bryan T.

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AU - Messina, Steven

AU - Kaufmann, Timothy

AU - Rickert, Jörn

AU - Brunner, Peter

AU - Worrell, Gregory A.

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Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model

Abstract

Keywords

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