Total hip replacement in patients with Down syndrome and degenerative osteoarthritis of the hip

D. F. Amanatullah, S. R. Rachala, R. T. Trousdale, R. J. Sierra

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Dysplasia of the hip, hypotonia, osteopenia, ligamentous laxity, and mental retardation increase the complexity of performing and managing patients with Down syndrome who require total hip replacement (THR). We identified 14 patients (six males, eight females, 21 hips) with Down syndrome and degenerative disease of the hip who underwent THR, with a minimum follow-up of two years from 1969 to 2009. In seven patients, bilateral THRs were performed while the rest had unilateral THRs. The mean clinical follow-up was 5.8 years (standard deviation (SD) 4.7; 2 to 17). The mean Harris hip score was 37.9 points (SD 7.8) preoperatively and increased to 89.2 (SD 12.3) at final follow-up (p = 1x10-9). No patient suffered a post-operative dislocation. In three patients, four hips had revision THR for aseptic loosening at a mean follow-up of 7.7 years (SD 6.3; 3 to 17). This rate of revision THR was higher than expected. Our patients with Down syndrome benefitted clinically from THR at mid-term follow-up.

Original languageEnglish (US)
Pages (from-to)1455-1458
Number of pages4
JournalBone and Joint Journal
Volume96B
Issue number11
DOIs
StatePublished - Nov 2014

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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