Topoisomerase II and the response to antileukemic therapy

Scott H. Kaufmann, Steven D. Gore, Carole B. Miller, Richard J. Jones, Leonard A. Zwelling, Erasmus Schneider, Philip J. Burke, Judith E. Karp

Research output: Contribution to journalReview article

25 Scopus citations

Abstract

A number of recent studies have investigated the expression of topoisomerase II in clinical leukemia specimens. Here we outline the rationale for these studies, identify potential pitfalls, summarize recent results, and discuss unanswered questions in this area.

Original languageEnglish (US)
Pages (from-to)217-237
Number of pages21
JournalLeukemia and Lymphoma
Volume29
Issue number3-4
DOIs
StatePublished - Jan 1 1998

Keywords

  • Antileukemic therapy
  • Response to therapy
  • Topoisomerase II

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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  • Cite this

    Kaufmann, S. H., Gore, S. D., Miller, C. B., Jones, R. J., Zwelling, L. A., Schneider, E., Burke, P. J., & Karp, J. E. (1998). Topoisomerase II and the response to antileukemic therapy. Leukemia and Lymphoma, 29(3-4), 217-237. https://doi.org/10.3109/10428199809068560