Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: A genomic perspective

Judith A. Jebanathirajah, Suraj Peri, Akhilesh Pandey

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.

Original languageEnglish (US)
Pages (from-to)388-391
Number of pages4
JournalTrends in Plant Science
Volume7
Issue number9
DOIs
StatePublished - Sep 1 2002

ASJC Scopus subject areas

  • Plant Science

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