Tissue adhesives and fibrin glues: NOVEMBER 2003

Bret Petersen; Alan Barkun; Steven Carpenter; Poonputt Chotiprasidhi; Ram Chuttani; William Silverman; Nadem Hussain; Julia Liu; Greta Taitelbaum; Gregory G. Ginsberg

doi:10.1016/S0016-5107(04)01564-0

Tissue adhesives and fibrin glues: NOVEMBER 2003

Bret Petersen, Alan Barkun, Steven Carpenter, Poonputt Chotiprasidhi, Ram Chuttani, William Silverman, Nadem Hussain, Julia Liu, Greta Taitelbaum, Gregory G. Ginsberg

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

92 Scopus citations

Abstract

Synthetic and biologic tissue glues have been used for control of bleeding and closure of fistulas and anastomotic leaks. GI endoscopic applications of cyanoacrylate and fibrin glues are considered "off-label" uses. Embolization and death have been reported with cyanoacrylate injection for hemostasis. Embolization also can occur from intravascular injection of thrombin or fibrin glue. Fibrin glue/thrombin can induce antibody formation with subsequent coagulopathy; however, this is a rare event with use of human-source blood products. There are insufficient data to support routine endoscopic use of the available preparations of cyanoacrylate, fibrin glue, and thrombin in clinical practice.

Original language	English (US)
Pages (from-to)	327-333
Number of pages	7
Journal	Gastrointestinal endoscopy
Volume	60
Issue number	3
DOIs	https://doi.org/10.1016/S0016-5107(04)01564-0
State	Published - Sep 2004

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

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10.1016/S0016-5107(04)01564-0

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title = "Tissue adhesives and fibrin glues: NOVEMBER 2003",

abstract = "Synthetic and biologic tissue glues have been used for control of bleeding and closure of fistulas and anastomotic leaks. GI endoscopic applications of cyanoacrylate and fibrin glues are considered {"}off-label{"} uses. Embolization and death have been reported with cyanoacrylate injection for hemostasis. Embolization also can occur from intravascular injection of thrombin or fibrin glue. Fibrin glue/thrombin can induce antibody formation with subsequent coagulopathy; however, this is a rare event with use of human-source blood products. There are insufficient data to support routine endoscopic use of the available preparations of cyanoacrylate, fibrin glue, and thrombin in clinical practice.",

author = "Bret Petersen and Alan Barkun and Steven Carpenter and Poonputt Chotiprasidhi and Ram Chuttani and William Silverman and Nadem Hussain and Julia Liu and Greta Taitelbaum and Ginsberg, {Gregory G.}",

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AU - Petersen, Bret

AU - Barkun, Alan

AU - Carpenter, Steven

AU - Chotiprasidhi, Poonputt

AU - Chuttani, Ram

AU - Silverman, William

AU - Hussain, Nadem

AU - Liu, Julia

AU - Taitelbaum, Greta

AU - Ginsberg, Gregory G.

PY - 2004/9

Y1 - 2004/9

N2 - Synthetic and biologic tissue glues have been used for control of bleeding and closure of fistulas and anastomotic leaks. GI endoscopic applications of cyanoacrylate and fibrin glues are considered "off-label" uses. Embolization and death have been reported with cyanoacrylate injection for hemostasis. Embolization also can occur from intravascular injection of thrombin or fibrin glue. Fibrin glue/thrombin can induce antibody formation with subsequent coagulopathy; however, this is a rare event with use of human-source blood products. There are insufficient data to support routine endoscopic use of the available preparations of cyanoacrylate, fibrin glue, and thrombin in clinical practice.

AB - Synthetic and biologic tissue glues have been used for control of bleeding and closure of fistulas and anastomotic leaks. GI endoscopic applications of cyanoacrylate and fibrin glues are considered "off-label" uses. Embolization and death have been reported with cyanoacrylate injection for hemostasis. Embolization also can occur from intravascular injection of thrombin or fibrin glue. Fibrin glue/thrombin can induce antibody formation with subsequent coagulopathy; however, this is a rare event with use of human-source blood products. There are insufficient data to support routine endoscopic use of the available preparations of cyanoacrylate, fibrin glue, and thrombin in clinical practice.

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Tissue adhesives and fibrin glues: NOVEMBER 2003

Abstract

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