Tipping the balance: MTDH-SND1 curbs oncogene-induced apoptosis and promotes tumorigenesis

Nagarajan Kannan, Connie J. Eaves

Research output: Contribution to journalShort survey

5 Scopus citations

Abstract

Tumorigenesis is a complex and poorly understood process in which oncogenes can activate competing proapoptotic and proneoplastic programs. A recent paper in Cancer Cell demonstrates a dual role of the MTDH-SND1 complex in suppressing the apoptotic response and promoting breast cancer development, suggesting a new therapeutic avenue.

Original languageEnglish (US)
Pages (from-to)118-120
Number of pages3
JournalCell Stem Cell
Volume15
Issue number2
DOIs
StatePublished - Aug 7 2014

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ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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