Time-resolved fluorescence techniques: methods and applications in biology

Franklyn G. Prendergast

Research output: Contribution to journalArticle

85 Scopus citations

Abstract

Modern time-resolved fluorescence spectroscopy affords detection and accurate quantification of fluorescence intensity decays as short as a few picoseconds. The method allows for measurements of dynamic events in the picosecond-nanosecond time frame. It is therefore especially useful for the study of macromolecular structure and dynamics, in particular for evaluating predictions from molecular dynamics simulations.

Original languageEnglish (US)
Pages (from-to)1054-1059
Number of pages6
JournalCurrent Opinion in Structural Biology
Volume1
Issue number6
DOIs
StatePublished - Dec 1991

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ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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