Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with graves disease

Adriane I. Budavari; Michael D. Whitaker; Richard A. Helmers

doi:10.4065/77.5.495

Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with graves disease

Adriane I. Budavari, Michael D. Whitaker, Richard A. Helmers

Endocrinology

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Graves disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. The autoantibodies mimic the effect of the hormone on thyroid cells, which stimulates autonomous production of thyroxine and triiodothyronine. It has been hypothesized that cross-reactivity of autoantibodies may result in Graves ophthalmopathy and dermopathy. A seldom-recognized feature of Graves disease is thymic hyperplasia. We report 2 patients with Graves disease and incidentally discovered anterior mediastinal masses presumed to be thymic hyperplasia. In both cases, these masses regressed spontaneously after treatment of hyperthyroidism.

Original language	English (US)
Article number	62220
Pages (from-to)	495-499
Number of pages	5
Journal	Mayo Clinic proceedings
Volume	77
Issue number	5
DOIs	https://doi.org/10.4065/77.5.495
State	Published - 2002

ASJC Scopus subject areas

General Medicine

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Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with graves disease

Abstract

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