Thumb carpometacarpal arthritis in patients with Ehlers-Danlos Syndrome: non-operative and operative experiences

Mario Hevesi, Arif R. Chaudhry, Eric R. Wagner, Steven Lawrence Moran

Research output: Contribution to journalArticle

Abstract

Ehlers-Danlos Syndrome is a connective tissue disorder that results in joint and generalized tissue hyperlaxity, predisposing patients to early onset arthritis. An institutional database spanning 1999–2016 was reviewed for all patients with symptomatic carpometacarpal arthritis and coexisting Ehlers-Danlos Syndrome, resulting in 14 thumbs amongst nine patients followed clinically for a median of 5.9 years (range 1–15). Patients managed non-operatively demonstrated stable subjective pain and trended towards decreased range of motion over time, whereas patients managed operatively had significant improvements in pain and trended towards increased grip strength. Our findings suggest that patients with Ehlers-Danlos-associated carpometacarpal arthritis can be successfully managed both operatively and non-operatively and that patients with pain refractory to conservative therapy may benefit from relief and increased hand strength following surgical intervention. Level of evidence: IV

Original languageEnglish (US)
JournalJournal of Hand Surgery: European Volume
DOIs
StateAccepted/In press - Jan 1 2018

Keywords

  • arthritis
  • Carpometacarpal joint
  • Ehlers-Danlos Syndrome
  • hand
  • surgical treatment

ASJC Scopus subject areas

  • Surgery

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