Thrombotic obstruction of disc valves

Clinical recognition and surgical management

George J. Kontos, Hartzell V Schaff, Thomas A. Orszulak, Francisco J. Puga, James R. Pluth, Gordon K. Danielson

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

Twenty-seven patients underwent reoperation because of thrombotic obstruction of a disc-typs cardiac valve prosthesis. Preoperative clinical features included effort dyspnea in 81%, new-onset angina in 44%, a new murmur in 89%, and an abnormal opening or closing sound associated with the prosthetic valve in 56%. Symptoms were present for 1 week or more before reoperation in 86%, although many patients were referred only after acute exacerbation of heart failure and development of pulmonary edema. Noninvasive studies confirmed prosthetic valve malfunction in only 33%, but cardiac catheterization documented thrombotic obstruction in all 15 patients in whom it was performed. In 14 of the 27 patients, prothrombin time was in the therapeutic range at the time of admission. Prompt reoperation for valve replacement or thrombectomy was performed with an operative mortality of 11%, and long-term outcome was satisfactory in all but 1 hospital survivor. These findings emphasize the importance of considering the diagnosis of thrombosed heart valves in patients with mechanical heart valves who are seen with nonspecific symptoms.

Original languageEnglish (US)
Pages (from-to)60-65
Number of pages6
JournalThe Annals of Thoracic Surgery
Volume48
Issue number1
DOIs
StatePublished - 1989

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Reoperation
Heart Valves
Heart Valve Prosthesis
Thrombectomy
Prothrombin Time
Pulmonary Edema
Cardiac Catheterization
Dyspnea
Survivors
Thrombosis
Heart Failure
Mortality
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Thrombotic obstruction of disc valves : Clinical recognition and surgical management. / Kontos, George J.; Schaff, Hartzell V; Orszulak, Thomas A.; Puga, Francisco J.; Pluth, James R.; Danielson, Gordon K.

In: The Annals of Thoracic Surgery, Vol. 48, No. 1, 1989, p. 60-65.

Research output: Contribution to journalArticle

Kontos, George J. ; Schaff, Hartzell V ; Orszulak, Thomas A. ; Puga, Francisco J. ; Pluth, James R. ; Danielson, Gordon K. / Thrombotic obstruction of disc valves : Clinical recognition and surgical management. In: The Annals of Thoracic Surgery. 1989 ; Vol. 48, No. 1. pp. 60-65.
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