@article{e17127c545a644b98d324dd6f4a4b3be,
title = "Thrombotic Microangiopathy Care Pathway: A Consensus Statement for the Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy (CAP-TMA) Disease-Oriented Group",
abstract = "Thrombotic microangiopathies (TMAs) comprise a heterogeneous set of conditions linked by a common histopathologic finding of endothelial damage resulting in microvascular thromboses and potentially serious complications. The typical clinical presentation is microangiopathic hemolytic anemia accompanied by thrombocytopenia with varying degrees of organ ischemia. The differential diagnoses are generally broad, while the workup is frequently complex and can be confusing. This statement represents the joint recommendations from a multidisciplinary team of Mayo Clinic physicians specializing in the management of TMA. It comprises a series of evidence- and consensus-based clinical pathways developed to allow a uniform approach to the spectrum of care including when to suspect TMA, what differential diagnoses to consider, which diagnostic tests to order, and how to provide initial empiric therapy, as well as some guidance on subsequent management.",
author = "Go, {Ronald S.} and Winters, {Jeffrey L.} and Nelson Leung and Murray, {David L.} and Willrich, {Maria A.} and Abraham, {Roshini S.} and Hatem Amer and Hogan, {William J.} and Marshall, {Ariela L.} and Sanjeev Sethi and Tran, {Cheryl L.} and Dong Chen and Pruthi, {Rajiv K.} and Ashrani, {Aneel A.} and Fervenza, {Fernando C.} and Cramer, {Carl H.} and Vilmarie Rodriguez and Wolanskyj, {Alexandra P.} and Thom{\'e}, {Stephan D.} and Hook, {C. Christopher} and Go, {Ronald S.} and Winters, {Jeffrey L.} and Nelson Leung and Murray, {David L.} and Willrich, {Maria A.} and Hatem Amer and Hogan, {William J.} and Marshall, {Ariela L.} and Sanjeev Sethi and Tran, {Cheryl L.} and Dong Chen and Pruthi, {Rajiv K.} and Ashrani, {Aneel A.} and Fervenza, {Fernando C.} and Cramer, {Carl H.} and Hook, {C. Christopher} and Garovic, {Vesna D.} and Yui, {Jennifer C.} and Botero, {Juliana Perez}",
note = "Funding Information: Grant Support: This work was supported by Mayo Clinic Division of Hematology. Publisher Copyright: {\textcopyright} 2016 Mayo Foundation for Medical Education and Research",
year = "2016",
month = sep,
day = "1",
doi = "10.1016/j.mayocp.2016.05.015",
language = "English (US)",
volume = "91",
pages = "1189--1211",
journal = "Mayo Clinic Proceedings",
issn = "0025-6196",
publisher = "Elsevier Science",
number = "9",
}