Abstract
What is the risk of thrombolysis in patients with acute stroke who might recover without treatment? In the National Institute of Neurological Disorders and Stroke rt-PA for Acute Stroke Trial, 2.6% of patients taking placebo showed spontaneous 24-hour recovery, compared to 11.5% of recombinant tissue-type plasminogen activator (rt-PA)-treated patients (p < 0.001). There were no symptomatic ICH in the patients taking placebo; one hypertensive, rt-PA-treated patient hemorrhaged. Assuming the National Institute of Neurological Disorders and Stroke protocol is followed rigorously, patients with acute stroke rarely recover spontaneously and the thrombolytic risk is low.
Original language | English (US) |
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Pages (from-to) | 2125-2128 |
Number of pages | 4 |
Journal | Neurology |
Volume | 57 |
Issue number | 11 |
DOIs | |
State | Published - Dec 11 2001 |
ASJC Scopus subject areas
- Clinical Neurology