Three-hand endoscopic endonasal transsphenoidal surgery: Experience with an anatomy-preserving mononostril approach technique

Chikezie I. Eseonu, Karim ReFaey, Eva Pamias-Portalatin, Javier Asensio, Oscar Garcia, Kofi D. Boahene, Alfredo Quinones-Hinojosa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

BACKGROUND: Variations on the endoscopic transsphenoidal approach present unique surgical techniques that have unique effects on surgical outcomes, extent of resection (EOR), and anatomical complications. OBJECTIVE: To analyze the learning curve and perioperative outcomes of the 3-hand endoscopic endonasal mononostril transsphenoidal technique. METHODS: Prospective case series and retrospective data analysis of patients who were treatedwith the 3-hand transsphenoidal technique between January 2007 andMay 2015 by a single neurosurgeon. Patient characteristics, preoperative presentation, tumor characteristics, operative times, learning curve, and postoperative outcomes were analyzed. Volumetric EOR was evaluated, and a logistic regression analysis was used to assess predictors of EOR. RESULTS: Two hundred seventy-five patients underwent an endoscopic transsphenoidal surgery using the 3-hand technique. One hundred eighteen patients in the early group had surgery between 2007 and 2010, while 157 patients in the late group had surgery between 2011 and 2015. Operative time was significantly shorter in the late group (161.6 min) compared to the early group (211.3min, P =.001). Both cohorts had similar EOR (early group 84.6% vs late group 85.5%, P =.846) and postoperative outcomes. The learning curve showed that it took 54 cases to achieve operative proficiency with the 3-handed technique. Multivariate modeling suggested that prior resections and preoperative tumor size are important predictors for EOR. CONCLUSION:We describe a 3-hand, mononostril endoscopic transsphenoidal technique performed by a single neurosurgeon that has minimal anatomic distortion and postoperative complications. During the learning curve of this technique, operative time can significantly decrease, while EOR, postoperative outcomes, and complications are not jeopardized.

Original languageEnglish (US)
Article numberopx110
Pages (from-to)158-165
Number of pages8
JournalOperative Neurosurgery
Volume14
Issue number2
DOIs
StatePublished - Feb 1 2018
Externally publishedYes

Fingerprint

Learning Curve
Anatomy
Hand
Operative Time
Neoplasms
Logistic Models
Regression Analysis
Neurosurgeons

Keywords

  • Learning curve
  • Mononostril
  • Pituitary adenoma
  • Transsphenoidal

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Three-hand endoscopic endonasal transsphenoidal surgery : Experience with an anatomy-preserving mononostril approach technique. / Eseonu, Chikezie I.; ReFaey, Karim; Pamias-Portalatin, Eva; Asensio, Javier; Garcia, Oscar; Boahene, Kofi D.; Quinones-Hinojosa, Alfredo.

In: Operative Neurosurgery, Vol. 14, No. 2, opx110, 01.02.2018, p. 158-165.

Research output: Contribution to journalArticle

Eseonu, Chikezie I. ; ReFaey, Karim ; Pamias-Portalatin, Eva ; Asensio, Javier ; Garcia, Oscar ; Boahene, Kofi D. ; Quinones-Hinojosa, Alfredo. / Three-hand endoscopic endonasal transsphenoidal surgery : Experience with an anatomy-preserving mononostril approach technique. In: Operative Neurosurgery. 2018 ; Vol. 14, No. 2. pp. 158-165.
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abstract = "BACKGROUND: Variations on the endoscopic transsphenoidal approach present unique surgical techniques that have unique effects on surgical outcomes, extent of resection (EOR), and anatomical complications. OBJECTIVE: To analyze the learning curve and perioperative outcomes of the 3-hand endoscopic endonasal mononostril transsphenoidal technique. METHODS: Prospective case series and retrospective data analysis of patients who were treatedwith the 3-hand transsphenoidal technique between January 2007 andMay 2015 by a single neurosurgeon. Patient characteristics, preoperative presentation, tumor characteristics, operative times, learning curve, and postoperative outcomes were analyzed. Volumetric EOR was evaluated, and a logistic regression analysis was used to assess predictors of EOR. RESULTS: Two hundred seventy-five patients underwent an endoscopic transsphenoidal surgery using the 3-hand technique. One hundred eighteen patients in the early group had surgery between 2007 and 2010, while 157 patients in the late group had surgery between 2011 and 2015. Operative time was significantly shorter in the late group (161.6 min) compared to the early group (211.3min, P =.001). Both cohorts had similar EOR (early group 84.6{\%} vs late group 85.5{\%}, P =.846) and postoperative outcomes. The learning curve showed that it took 54 cases to achieve operative proficiency with the 3-handed technique. Multivariate modeling suggested that prior resections and preoperative tumor size are important predictors for EOR. CONCLUSION:We describe a 3-hand, mononostril endoscopic transsphenoidal technique performed by a single neurosurgeon that has minimal anatomic distortion and postoperative complications. During the learning curve of this technique, operative time can significantly decrease, while EOR, postoperative outcomes, and complications are not jeopardized.",
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T2 - Experience with an anatomy-preserving mononostril approach technique

AU - Eseonu, Chikezie I.

AU - ReFaey, Karim

AU - Pamias-Portalatin, Eva

AU - Asensio, Javier

AU - Garcia, Oscar

AU - Boahene, Kofi D.

AU - Quinones-Hinojosa, Alfredo

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N2 - BACKGROUND: Variations on the endoscopic transsphenoidal approach present unique surgical techniques that have unique effects on surgical outcomes, extent of resection (EOR), and anatomical complications. OBJECTIVE: To analyze the learning curve and perioperative outcomes of the 3-hand endoscopic endonasal mononostril transsphenoidal technique. METHODS: Prospective case series and retrospective data analysis of patients who were treatedwith the 3-hand transsphenoidal technique between January 2007 andMay 2015 by a single neurosurgeon. Patient characteristics, preoperative presentation, tumor characteristics, operative times, learning curve, and postoperative outcomes were analyzed. Volumetric EOR was evaluated, and a logistic regression analysis was used to assess predictors of EOR. RESULTS: Two hundred seventy-five patients underwent an endoscopic transsphenoidal surgery using the 3-hand technique. One hundred eighteen patients in the early group had surgery between 2007 and 2010, while 157 patients in the late group had surgery between 2011 and 2015. Operative time was significantly shorter in the late group (161.6 min) compared to the early group (211.3min, P =.001). Both cohorts had similar EOR (early group 84.6% vs late group 85.5%, P =.846) and postoperative outcomes. The learning curve showed that it took 54 cases to achieve operative proficiency with the 3-handed technique. Multivariate modeling suggested that prior resections and preoperative tumor size are important predictors for EOR. CONCLUSION:We describe a 3-hand, mononostril endoscopic transsphenoidal technique performed by a single neurosurgeon that has minimal anatomic distortion and postoperative complications. During the learning curve of this technique, operative time can significantly decrease, while EOR, postoperative outcomes, and complications are not jeopardized.

AB - BACKGROUND: Variations on the endoscopic transsphenoidal approach present unique surgical techniques that have unique effects on surgical outcomes, extent of resection (EOR), and anatomical complications. OBJECTIVE: To analyze the learning curve and perioperative outcomes of the 3-hand endoscopic endonasal mononostril transsphenoidal technique. METHODS: Prospective case series and retrospective data analysis of patients who were treatedwith the 3-hand transsphenoidal technique between January 2007 andMay 2015 by a single neurosurgeon. Patient characteristics, preoperative presentation, tumor characteristics, operative times, learning curve, and postoperative outcomes were analyzed. Volumetric EOR was evaluated, and a logistic regression analysis was used to assess predictors of EOR. RESULTS: Two hundred seventy-five patients underwent an endoscopic transsphenoidal surgery using the 3-hand technique. One hundred eighteen patients in the early group had surgery between 2007 and 2010, while 157 patients in the late group had surgery between 2011 and 2015. Operative time was significantly shorter in the late group (161.6 min) compared to the early group (211.3min, P =.001). Both cohorts had similar EOR (early group 84.6% vs late group 85.5%, P =.846) and postoperative outcomes. The learning curve showed that it took 54 cases to achieve operative proficiency with the 3-handed technique. Multivariate modeling suggested that prior resections and preoperative tumor size are important predictors for EOR. CONCLUSION:We describe a 3-hand, mononostril endoscopic transsphenoidal technique performed by a single neurosurgeon that has minimal anatomic distortion and postoperative complications. During the learning curve of this technique, operative time can significantly decrease, while EOR, postoperative outcomes, and complications are not jeopardized.

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KW - Mononostril

KW - Pituitary adenoma

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