Three dimensional in vitro mechanical model for bone formation

A. C. Jen, S. L. Ishaug, Michael J Yaszemski, L. V. McIntire, A. G. Mikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A three dimensional in vitro model was developed to study the effects of mechanical stimuli on bone formation. The model takes advantage of the simplicity of cell culture with an isolated cell population which allows the investigation of the cellular and molecular mechanisms while maintaining the natural architecture of bone. Three dimensional polymer/cell cultures were subjected to controlled compression to simulate mechanical loading conditions, and bone formation was monitored by cellular activity and structural observation, confocal microscopy and histology.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors Anon
Place of PublicationSt. Louis Park, MN, United States
PublisherSoc for Biomaterials
Pages979
Number of pages1
Volume1
StatePublished - 1996
Externally publishedYes
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

Fingerprint

Bone
Cell culture
Histology
Confocal microscopy
Polymers
Compaction
Cells

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Jen, A. C., Ishaug, S. L., Yaszemski, M. J., McIntire, L. V., & Mikos, A. G. (1996). Three dimensional in vitro mechanical model for bone formation. In Anon (Ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 1, pp. 979). St. Louis Park, MN, United States: Soc for Biomaterials.

Three dimensional in vitro mechanical model for bone formation. / Jen, A. C.; Ishaug, S. L.; Yaszemski, Michael J; McIntire, L. V.; Mikos, A. G.

Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. ed. / Anon. Vol. 1 St. Louis Park, MN, United States : Soc for Biomaterials, 1996. p. 979.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jen, AC, Ishaug, SL, Yaszemski, MJ, McIntire, LV & Mikos, AG 1996, Three dimensional in vitro mechanical model for bone formation. in Anon (ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. vol. 1, Soc for Biomaterials, St. Louis Park, MN, United States, pp. 979, Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, 5/29/96.
Jen AC, Ishaug SL, Yaszemski MJ, McIntire LV, Mikos AG. Three dimensional in vitro mechanical model for bone formation. In Anon, editor, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. Vol. 1. St. Louis Park, MN, United States: Soc for Biomaterials. 1996. p. 979
Jen, A. C. ; Ishaug, S. L. ; Yaszemski, Michael J ; McIntire, L. V. ; Mikos, A. G. / Three dimensional in vitro mechanical model for bone formation. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. editor / Anon. Vol. 1 St. Louis Park, MN, United States : Soc for Biomaterials, 1996. pp. 979
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