Thoracoamniotic shunting for fetal pleural effusions with hydrops

Olivier Picone, Alexandra Benachi, Laurent Mandelbrot, Rodrigo Ruano, Yves Dumez, Marc Dommergues

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

The purpose of this study was to evaluate perinatal outcome after thoracoamniotic shunting for fetal pleural effusions with hydrops. This was a retrospective study. Shunting was performed immediately after diagnosis and was successful in all 54 of the cases that were attempted. There were 7 pregnancy terminations, 9 in utero deaths, and 38 live births, of which 7 children died in the neonatal period and 31 children survived. Among the liveborn infants, 27 infants were delivered preterm (71%), of whom 7 infants (15%) had preterm premature rupture of membranes and 4 infants (8.5%) had chorioamnionitis. Perinatal death (23/54 infants; 43%) was related to underlying anomalies (7 cases), pulmonary hypoplasia (5 cases), chorioamnionitis (2 cases), or treatment failure for unknown reasons (9 cases). All 31 survivors had chylothorax; for 28 of the survivors, the chylothorax was primary, and for 3 survivors, the chylothorax was the result of right congenital diaphragmatic hernia, pulmonary sequestration, or Noonan syndrome. After the shunting, pleural effusion with hydrops has a 57% survival rate; premature delivery is the leading source of morbidity.

Original languageEnglish (US)
Pages (from-to)2047-2050
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume191
Issue number6
DOIs
StatePublished - Dec 1 2004
Externally publishedYes

Fingerprint

Pleural Effusion
Edema
Chylothorax
Chorioamnionitis
Survivors
Noonan Syndrome
Bronchopulmonary Sequestration
Live Birth
Treatment Failure
Survival Rate
Retrospective Studies
Morbidity
Pregnancy
Lung

Keywords

  • Chylothorax
  • Fetal therapy
  • Hydrops
  • Pleural effusion
  • Thoracoamniotic shunt

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Thoracoamniotic shunting for fetal pleural effusions with hydrops. / Picone, Olivier; Benachi, Alexandra; Mandelbrot, Laurent; Ruano, Rodrigo; Dumez, Yves; Dommergues, Marc.

In: American Journal of Obstetrics and Gynecology, Vol. 191, No. 6, 01.12.2004, p. 2047-2050.

Research output: Contribution to journalArticle

Picone, Olivier ; Benachi, Alexandra ; Mandelbrot, Laurent ; Ruano, Rodrigo ; Dumez, Yves ; Dommergues, Marc. / Thoracoamniotic shunting for fetal pleural effusions with hydrops. In: American Journal of Obstetrics and Gynecology. 2004 ; Vol. 191, No. 6. pp. 2047-2050.
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