Thoracoamniotic shunting for fetal pleural effusions with hydrops

Olivier Picone, Alexandra Benachi, Laurent Mandelbrot, Rodrigo Ruano, Yves Dumez, Marc Dommergues

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

The purpose of this study was to evaluate perinatal outcome after thoracoamniotic shunting for fetal pleural effusions with hydrops. This was a retrospective study. Shunting was performed immediately after diagnosis and was successful in all 54 of the cases that were attempted. There were 7 pregnancy terminations, 9 in utero deaths, and 38 live births, of which 7 children died in the neonatal period and 31 children survived. Among the liveborn infants, 27 infants were delivered preterm (71%), of whom 7 infants (15%) had preterm premature rupture of membranes and 4 infants (8.5%) had chorioamnionitis. Perinatal death (23/54 infants; 43%) was related to underlying anomalies (7 cases), pulmonary hypoplasia (5 cases), chorioamnionitis (2 cases), or treatment failure for unknown reasons (9 cases). All 31 survivors had chylothorax; for 28 of the survivors, the chylothorax was primary, and for 3 survivors, the chylothorax was the result of right congenital diaphragmatic hernia, pulmonary sequestration, or Noonan syndrome. After the shunting, pleural effusion with hydrops has a 57% survival rate; premature delivery is the leading source of morbidity.

Original languageEnglish (US)
Pages (from-to)2047-2050
Number of pages4
JournalAmerican journal of obstetrics and gynecology
Volume191
Issue number6
DOIs
StatePublished - Dec 1 2004

Keywords

  • Chylothorax
  • Fetal therapy
  • Hydrops
  • Pleural effusion
  • Thoracoamniotic shunt

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Thoracoamniotic shunting for fetal pleural effusions with hydrops'. Together they form a unique fingerprint.

Cite this