Thiopurine S-Methyltransferase Pharmacogenomics: Protein Misfolding, Aggregation, and Degradation

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationProtein Misfolding Diseases
Subtitle of host publicationCurrent and Emerging Principles and Therapies
PublisherJohn Wiley and Sons
Pages453-468
Number of pages16
ISBN (Print)9780471799283
DOIs
StatePublished - Jul 2 2010

Keywords

  • Pharmacogenomics, study of the role of inheritance in individual variation in drug response
  • TPMT pharmacogenomics - mechanisms of degradation
  • Thiopurine S-methyltransferase (TPMT) pharmacogenomics - protein misfolding, aggregation and degradation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Li, F., & Weinshilboum, R. M. (2010). Thiopurine S-Methyltransferase Pharmacogenomics: Protein Misfolding, Aggregation, and Degradation. In Protein Misfolding Diseases: Current and Emerging Principles and Therapies (pp. 453-468). John Wiley and Sons. https://doi.org/10.1002/9780470572702.ch20