Abstract
The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.
Original language | English (US) |
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Pages (from-to) | 373-376 |
Number of pages | 4 |
Journal | Journal of Magnetism and Magnetic Materials |
Volume | 321 |
Issue number | 5 |
DOIs | |
State | Published - Mar 2009 |
Keywords
- Cetyl alcohol
- Cyclohexane
- Magnetic nanoparticles
- Thermal release
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics