Thermal response of superparamagnetic particles suspended in liquid and solid media

Pengyun Zeng, Timothy L. Kline, Jian ping Wang, Timothy Scott Wiedmann

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The purpose of this study was to explore the properties of coated superparamagnetic nanoparticles (SPNs) specifically for their use in thermal-responsive drug delivery systems. Coated, magnetite SPNs were prepared and dispersed in cyclohexane or cetyl alcohol, a solid lipid at the physiological temperatures of 37 °C. The induced temperature change as a function of SPN concentration and external magnetic field and frequency was consistent with theoretical predictions. SPNs dispersed in a solid lipid matrix underwent heating and the associated melting occurred at a temperature suitable for a thermal-responsive drug delivery system.

Original languageEnglish (US)
Pages (from-to)373-376
Number of pages4
JournalJournal of Magnetism and Magnetic Materials
Volume321
Issue number5
DOIs
StatePublished - Mar 1 2009

Keywords

  • Cetyl alcohol
  • Cyclohexane
  • Magnetic nanoparticles
  • Thermal release

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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