Thermal ablative therapies and immune checkpoint modulation: Can locoregional approaches effect a systemic response?

Amol Mehta, Rahmi Oklu, Rahul A. Sheth

Research output: Contribution to journalReview article

28 Scopus citations

Abstract

Percutaneous image-guided ablation is an increasingly common treatment for a multitude of solid organ malignancies. While historically these techniques have been restricted to the management of small, unresectable tumors, there is an expanding appreciation for the systemic effects these locoregional interventions can cause. In this review, we summarize the mechanisms of action for the most common thermal ablation modalities and highlight the key advances in knowledge regarding the interactions between thermal ablation and the immune system.

Original languageEnglish (US)
Article number9251375
JournalGastroenterology Research and Practice
Volume2016
DOIs
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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