Abstract
The T2-FLAIR mismatch sign, in which a low-grade glioma is hyperintense on T2-weighted MR and centrally hypointense on T2-weighted FLAIR MR, has been reported as 100% specific for IDH-mutant astrocytomas in several series. We report several cases of “false positive” T2-FLAIR mismatch sign occurring outside the context of IDH-mutant astrocytomas, predominantly in children or young adults with pediatric-type gliomas. These results suggest caution in the interpretation of the T2-FLAIR mismatch sign in the pediatric glioma population.
Original language | English (US) |
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Pages (from-to) | 225-227 |
Number of pages | 3 |
Journal | Neuroradiology |
Volume | 61 |
Issue number | 2 |
DOIs | |
State | Published - Feb 11 2019 |
Keywords
- FLAIR
- Glioma
- IDH-mutation
- MRI
- Mismatch
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
- Cardiology and Cardiovascular Medicine