Mantle cell lymphoma (MCL) is a mature B-cell lymphoma associated with the hallmark translocation t(11;14)(q13;32), which involves the cyclin D1 (CCND1) and immunoglobin heavy chain (IgH) genes. It may transform to a more aggressive blastoid or pleomorphic variant, with or without acquisition of chromosomal abnormalities. MCL could also present with a leukemic phase with marked lymphocytosis. A literature search did not reveal any prior reports of MCL transforming to or followed by a B-cell lymphoblastic leukemia (B-ALL).
|Original language||English (US)|
|Number of pages||5|
|Journal||International Journal of Clinical and Experimental Pathology|
|State||Published - Jan 1 2014|
ASJC Scopus subject areas
- Pathology and Forensic Medicine