Therapeutic Applications of Invasive Neuromodulation in Children and Adolescents

Deniz Doruk Camsari, Melissa Kirkovski, Paul E Croarkin

Research output: Contribution to journalArticle

Abstract

Although the application of noninvasive brain stimulation methods to children and adolescents has been frequently studied in depression, autism spectrum disorder, attention-deficit/hyperactivity disorder, and other neuropsychiatric disorders, invasive methods such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) have received less attention. DBS and VNS have demonstrated utility in young patients especially for dystonia and epilepsy. VNS has FDA clearance for intractable epilepsy in patients aged 4 years and older. Further measured work with invasive neuromodulation for children and adolescents with debilitating neuropsychiatric disorders could provide new treatment options and expand current knowledge base of neurocircuitry across development.

Original languageEnglish (US)
JournalPsychiatric Clinics of North America
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Vagus Nerve Stimulation
Deep Brain Stimulation
Knowledge Bases
Dystonia
Attention Deficit Disorder with Hyperactivity
Epilepsy
Therapeutics
Depression
Brain

Keywords

  • Adolescents
  • Children
  • DBS
  • Deep brain stimulation
  • Invasive brain stimulation
  • Neuromodulation
  • Vagal nerve stimulation
  • VNS

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Therapeutic Applications of Invasive Neuromodulation in Children and Adolescents. / Doruk Camsari, Deniz; Kirkovski, Melissa; Croarkin, Paul E.

In: Psychiatric Clinics of North America, 01.01.2018.

Research output: Contribution to journalArticle

@article{342c279b588a4032b5a12ca08f5b3bc8,
title = "Therapeutic Applications of Invasive Neuromodulation in Children and Adolescents",
abstract = "Although the application of noninvasive brain stimulation methods to children and adolescents has been frequently studied in depression, autism spectrum disorder, attention-deficit/hyperactivity disorder, and other neuropsychiatric disorders, invasive methods such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) have received less attention. DBS and VNS have demonstrated utility in young patients especially for dystonia and epilepsy. VNS has FDA clearance for intractable epilepsy in patients aged 4 years and older. Further measured work with invasive neuromodulation for children and adolescents with debilitating neuropsychiatric disorders could provide new treatment options and expand current knowledge base of neurocircuitry across development.",
keywords = "Adolescents, Children, DBS, Deep brain stimulation, Invasive brain stimulation, Neuromodulation, Vagal nerve stimulation, VNS",
author = "{Doruk Camsari}, Deniz and Melissa Kirkovski and Croarkin, {Paul E}",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.psc.2018.04.008",
language = "English (US)",
journal = "Psychiatric Clinics of North America",
issn = "0193-953X",
publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - Therapeutic Applications of Invasive Neuromodulation in Children and Adolescents

AU - Doruk Camsari, Deniz

AU - Kirkovski, Melissa

AU - Croarkin, Paul E

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Although the application of noninvasive brain stimulation methods to children and adolescents has been frequently studied in depression, autism spectrum disorder, attention-deficit/hyperactivity disorder, and other neuropsychiatric disorders, invasive methods such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) have received less attention. DBS and VNS have demonstrated utility in young patients especially for dystonia and epilepsy. VNS has FDA clearance for intractable epilepsy in patients aged 4 years and older. Further measured work with invasive neuromodulation for children and adolescents with debilitating neuropsychiatric disorders could provide new treatment options and expand current knowledge base of neurocircuitry across development.

AB - Although the application of noninvasive brain stimulation methods to children and adolescents has been frequently studied in depression, autism spectrum disorder, attention-deficit/hyperactivity disorder, and other neuropsychiatric disorders, invasive methods such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) have received less attention. DBS and VNS have demonstrated utility in young patients especially for dystonia and epilepsy. VNS has FDA clearance for intractable epilepsy in patients aged 4 years and older. Further measured work with invasive neuromodulation for children and adolescents with debilitating neuropsychiatric disorders could provide new treatment options and expand current knowledge base of neurocircuitry across development.

KW - Adolescents

KW - Children

KW - DBS

KW - Deep brain stimulation

KW - Invasive brain stimulation

KW - Neuromodulation

KW - Vagal nerve stimulation

KW - VNS

UR - http://www.scopus.com/inward/record.url?scp=85049894043&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049894043&partnerID=8YFLogxK

U2 - 10.1016/j.psc.2018.04.008

DO - 10.1016/j.psc.2018.04.008

M3 - Article

C2 - 30098659

AN - SCOPUS:85049894043

JO - Psychiatric Clinics of North America

JF - Psychiatric Clinics of North America

SN - 0193-953X

ER -