The use of stereotactic radiosurgery for the treatment of spinal axis tumors: A review

Mohamad Bydon, Rafael De La Garza-Ramos, Chetan Bettagowda, Ziya L. Gokaslan, Daniel M. Sciubba

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

As the prevalence of cancer in the general population increases, a greater proportion of patients will present with symptomatic metastatic lesions to the spine. While surgery has been historically considered the treatment of choice for spinal cord/nerve root compression, mechanical instability and intractable pain, radiation therapy - particularly stereotactic radiosurgery (SRS) - has been increasingly used as either a primary or adjuvant treatment modality. In this manuscript, the authors perform a review on the principles behind SRS and its use in the treatment of spinal tumors, specifically primary and secondary malignant tumors. In the last decades, numerous retrospective studies have shown the feasibility of SRS as both primary treatment for malignant tumors, as well as adjuvant treatment following surgical resection. Although local control rates may reach 90%, future studies are warranted to determine optimal doses, fractionation of therapy and the long-term implications of irradiation to neural structures.

Original languageEnglish (US)
Pages (from-to)166-172
Number of pages7
JournalClinical Neurology and Neurosurgery
Volume125
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Radiosurgery
Neoplasms
Therapeutics
Dose Fractionation
Intractable Pain
Radiculopathy
Spinal Nerve Roots
Spinal Cord
Spine
Radiotherapy
Retrospective Studies
Population

Keywords

  • Spinal metastases
  • Spinal surgery
  • Spinal tumor
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

The use of stereotactic radiosurgery for the treatment of spinal axis tumors : A review. / Bydon, Mohamad; De La Garza-Ramos, Rafael; Bettagowda, Chetan; Gokaslan, Ziya L.; Sciubba, Daniel M.

In: Clinical Neurology and Neurosurgery, Vol. 125, 2014, p. 166-172.

Research output: Contribution to journalReview article

Bydon, Mohamad ; De La Garza-Ramos, Rafael ; Bettagowda, Chetan ; Gokaslan, Ziya L. ; Sciubba, Daniel M. / The use of stereotactic radiosurgery for the treatment of spinal axis tumors : A review. In: Clinical Neurology and Neurosurgery. 2014 ; Vol. 125. pp. 166-172.
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