The Use of Fine-Needle Aspiration in the Diagnosis of Metastatic Pulmonary Adenoid Cystic Carcinoma

Martha Bishop Pitman, Mark E. Sherman, W. Stephen Black-Schaffer

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Nine patients with a history of adenoid cystic carcinoma (ACC) arising in the head and neck and in whom transthoracic fine-needle aspiration (FNA) was performed to investigate pulmonary lesions are described. FNA yielded a definitive diagnosis of metastatic ACC in all cases. In six of the nine patients, the pulmonary metastases were asymptomatic. Lung lesions were discovered up to 19 years after primary tumor presentation, and in two, pulmonary spread was the only evidence of recurrent disease. On the basis of the FNA diagnosis, these two patients were treated surgically for their isolated pulmonary metastases, and are disease free at 107 and 139 months. Six of the nine patients received radiation or chemotherapy; one initially refused treatment. Thoracotomy was avoided in these patients on the basis of the FNA diagnosis. All are alive with disease at 25 to 246 months. The metastatic tumors were indistinguishable cytologically from two primary pulmonary ACCs that were available for comparison. Our experience suggests FNA is a useful tool in the diagnosis of ACC in pulmonary material—one which obviates the need for thoracotomy with its associated morbidity.

Original languageEnglish (US)
Pages (from-to)441-447
Number of pages7
JournalOtolaryngology-Head and Neck Surgery
Volume104
Issue number4
DOIs
StatePublished - 1991
Externally publishedYes

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Adenoid Cystic Carcinoma
Fine Needle Biopsy
Lung
Thoracotomy
Neoplasm Metastasis
Lung Diseases
Neoplasms
Neck
Head
Radiation
Morbidity
Drug Therapy

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

The Use of Fine-Needle Aspiration in the Diagnosis of Metastatic Pulmonary Adenoid Cystic Carcinoma. / Pitman, Martha Bishop; Sherman, Mark E.; Black-Schaffer, W. Stephen.

In: Otolaryngology-Head and Neck Surgery, Vol. 104, No. 4, 1991, p. 441-447.

Research output: Contribution to journalArticle

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