The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department

Peter A. Kavsak; Alice M. Newman; Dennis T. Ko; Andrew R. MacRae; Allan S. Jaffe

doi:10.1016/j.clinbiochem.2009.11.004

The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department

Peter A. Kavsak, Alice M. Newman, Dennis T. Ko, Andrew R. MacRae, Allan S. Jaffe

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Objective: To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. Design and methods: In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (- 70 °C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement. Results: Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with ≤ two cytokines elevated. Discussion: A cytokine panel might be useful for risk stratification for HF/death.

Original language	English (US)
Pages (from-to)	505-507
Number of pages	3
Journal	Clinical Biochemistry
Volume	43
Issue number	4-5
DOIs	https://doi.org/10.1016/j.clinbiochem.2009.11.004
State	Published - Mar 2010

Keywords

Acute coronary syndrome
Cytokine panel
Heart failure
Risk stratification, ED

ASJC Scopus subject areas

Clinical Biochemistry

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10.1016/j.clinbiochem.2009.11.004

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title = "The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department",

abstract = "Objective: To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. Design and methods: In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (- 70 °C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement. Results: Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with ≤ two cytokines elevated. Discussion: A cytokine panel might be useful for risk stratification for HF/death.",

keywords = "Acute coronary syndrome, Cytokine panel, Heart failure, Risk stratification, ED",

author = "Kavsak, {Peter A.} and Newman, {Alice M.} and Ko, {Dennis T.} and MacRae, {Andrew R.} and Jaffe, {Allan S.}",

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AU - Kavsak, Peter A.

AU - Newman, Alice M.

AU - Ko, Dennis T.

AU - MacRae, Andrew R.

AU - Jaffe, Allan S.

PY - 2010/3

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N2 - Objective: To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. Design and methods: In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (- 70 °C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement. Results: Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with ≤ two cytokines elevated. Discussion: A cytokine panel might be useful for risk stratification for HF/death.

AB - Objective: To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. Design and methods: In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (- 70 °C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement. Results: Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with ≤ two cytokines elevated. Discussion: A cytokine panel might be useful for risk stratification for HF/death.

KW - Acute coronary syndrome

KW - Cytokine panel

KW - Heart failure

KW - Risk stratification, ED

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The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department

Abstract

Keywords

ASJC Scopus subject areas

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