The Speed of Sound and Attenuation of an IEC Agar-Based Tissue-Mimicking Material for High Frequency Ultrasound Applications

Chao Sun, Stephen D. Pye, Jacinta E. Browne, Anna Janeczko, Bill Ellis, Mairead B. Butler, Vassilis Sboros, Adrian J.W. Thomson, Mark P. Brewin, Charles H. Earnshaw, Carmel M. Moran

Research output: Contribution to journalArticlepeer-review

Abstract

This study characterized the acoustic properties of an International Electromechanical Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the range 10-47 MHz. A broadband reflection substitution technique was employed using two independent systems at 21°C ± 1°C. Using a commercially available preclinical ultrasound scanner and a scanning acoustic macroscope, the measured speeds of sound were 1547.4 ± 1.4 m.s -1 and 1548.0 ± 6.1 m.s -1, respectively, and were approximately constant over the frequency range. The measured attenuation (dB.cm -1) was found to vary with frequency f (MHz) as 0.40f + 0.0076f 2. Using this polynomial equation and extrapolating to lower frequencies give values comparable to those published at lower frequencies and can estimate the attenuation of this TMM in the frequency range up to 47 MHz. This characterisation enhances understanding in the use of this TMM as a tissue equivalent material for high frequency ultrasound applications.

Original languageEnglish (US)
Pages (from-to)1262-1270
Number of pages9
JournalUltrasound in Medicine and Biology
Volume38
Issue number7
DOIs
StatePublished - Jul 2012

Keywords

  • Attenuation
  • Frequency dependence
  • High frequency
  • Speed of sound
  • Tissue mimicking material
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

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