The safety of weekly plateletpheresis: effect on the donors' lymphocyte population

J. A. Koepke, W. M. Parks, J. A. Goeken, G. G. Klee, R. G. Strauss

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

Ten normal donors were monitored before, during, and after ten weekly donations of platelet concentrates prepared using the Haemonetics Model 30 blood processor. Analysis of these data indicates about a 20 per cent decrease of lymphocytes, with B cells being significantly decreased in half of these patients. While coincident immunoglobulin deficiencies did not develop in this short‐term study, it is presumed that these would occur with a prolongation of platelet donations, as has been noted in previous studies. Additional studies are indicated to further delineate the lymphocyte depletion in normal platelet donors. 1981 AABB

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalTransfusion
Volume21
Issue number1
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Hematology

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    Koepke, J. A., Parks, W. M., Goeken, J. A., Klee, G. G., & Strauss, R. G. (1981). The safety of weekly plateletpheresis: effect on the donors' lymphocyte population. Transfusion, 21(1), 59-63. https://doi.org/10.1046/j.1537-2995.1981.21181127485.x