The safety of weekly plateletpheresis: Effect on the donors' lymphocyte population

J. A. Koepke, W. M. Parks, J. A. Goeken, G. G. Klee, R. G. Strauss

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Ten normal donors were monitored before, during, and after ten weekly donations of platelet concentrates prepared using the Haemonetics Model 30 blood processor. Analysis of these data indicates about a 20 percent decrease of lymphocytes, with B cells being significantly decreased in half of these patients. While coincident immunoglobulin deficiencies did not develop in this short-term study, it is presumed that these would occur with a prolongation of platelet donations, as has been noted in previous studies. Additional studies are indicated to further delineate the lymphocyte depletion in normal platelet donors.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalTransfusion
Volume21
Issue number1
StatePublished - 1981
Externally publishedYes

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Plateletpheresis
Blood Platelets
Tissue Donors
Lymphocytes
Safety
Lymphocyte Depletion
Population
Immunoglobulins
B-Lymphocytes

ASJC Scopus subject areas

  • Hematology
  • Immunology

Cite this

Koepke, J. A., Parks, W. M., Goeken, J. A., Klee, G. G., & Strauss, R. G. (1981). The safety of weekly plateletpheresis: Effect on the donors' lymphocyte population. Transfusion, 21(1), 59-63.

The safety of weekly plateletpheresis : Effect on the donors' lymphocyte population. / Koepke, J. A.; Parks, W. M.; Goeken, J. A.; Klee, G. G.; Strauss, R. G.

In: Transfusion, Vol. 21, No. 1, 1981, p. 59-63.

Research output: Contribution to journalArticle

Koepke, JA, Parks, WM, Goeken, JA, Klee, GG & Strauss, RG 1981, 'The safety of weekly plateletpheresis: Effect on the donors' lymphocyte population', Transfusion, vol. 21, no. 1, pp. 59-63.
Koepke JA, Parks WM, Goeken JA, Klee GG, Strauss RG. The safety of weekly plateletpheresis: Effect on the donors' lymphocyte population. Transfusion. 1981;21(1):59-63.
Koepke, J. A. ; Parks, W. M. ; Goeken, J. A. ; Klee, G. G. ; Strauss, R. G. / The safety of weekly plateletpheresis : Effect on the donors' lymphocyte population. In: Transfusion. 1981 ; Vol. 21, No. 1. pp. 59-63.
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