Abstract
Epidemiological data of phytoestrogens and prostate cancer strongly supports the cancer protective effects of isoflavones found in soy products. Inhibition of cell proliferation via hormone-dependent and hormone-independent mechanisms by soy phytochemicals has been studied extensively in cell culture and animal studies. Herein, we review the current literature on the epidemiology and effects of two soy phytoestrogens, genistein and daidzein, and would stress the need for controlled human trials to assess the true preventive and therapeutic effects of these compounds.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 71-81 |
| Number of pages | 11 |
| Journal | Urologic Clinics of North America |
| Volume | 29 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2002 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Urology
Cite this
The role of soy phytoestrogens in prostate cancer. / Castle, Erik P; Thrasher, J. Brantley.
In: Urologic Clinics of North America, Vol. 29, No. 1, 2002, p. 71-81.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The role of soy phytoestrogens in prostate cancer
AU - Castle, Erik P
AU - Thrasher, J. Brantley
PY - 2002
Y1 - 2002
N2 - Epidemiological data of phytoestrogens and prostate cancer strongly supports the cancer protective effects of isoflavones found in soy products. Inhibition of cell proliferation via hormone-dependent and hormone-independent mechanisms by soy phytochemicals has been studied extensively in cell culture and animal studies. Herein, we review the current literature on the epidemiology and effects of two soy phytoestrogens, genistein and daidzein, and would stress the need for controlled human trials to assess the true preventive and therapeutic effects of these compounds.
AB - Epidemiological data of phytoestrogens and prostate cancer strongly supports the cancer protective effects of isoflavones found in soy products. Inhibition of cell proliferation via hormone-dependent and hormone-independent mechanisms by soy phytochemicals has been studied extensively in cell culture and animal studies. Herein, we review the current literature on the epidemiology and effects of two soy phytoestrogens, genistein and daidzein, and would stress the need for controlled human trials to assess the true preventive and therapeutic effects of these compounds.
UR - http://www.scopus.com/inward/record.url?scp=0036301887&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036301887&partnerID=8YFLogxK
U2 - 10.1016/S0094-0143(02)00019-8
DO - 10.1016/S0094-0143(02)00019-8
M3 - Article
C2 - 12109358
AN - SCOPUS:0036301887
VL - 29
SP - 71
EP - 81
JO - Urologic Clinics of North America
JF - Urologic Clinics of North America
SN - 0094-0143
IS - 1
ER -