The role of precuneus and left inferior frontal cortex during source memory episodic retrieval

Brian Nils Lundstrom, Martin Ingvar, Karl Magnus Petersson

Research output: Contribution to journalArticlepeer-review

235 Scopus citations

Abstract

The posterior medial parietal cortex and left prefrontal cortex (PFC) have both been implicated in the recollection of past episodes. In a previous study, we found the posterior precuneus and left lateral inferior frontal cortex to be activated during episodic source memory retrieval. This study further examines the role of posterior precuneal and left prefrontal activation during episodic source memory retrieval using a similar source memory paradigm but with longer latency between encoding and retrieval. Our results suggest that both the precuneus and the left inferior PFC are important for regeneration of rich episodic contextual associations and that the precuneus activates in tandem with the left inferior PFC during correct source retrieval. Further, results suggest that the left ventro-lateral frontal region/frontal operculum is involved in searching for task-relevant information (BA 47) and subsequent monitoring or scrutiny (BA 44/45) while regions in the dorsal inferior frontal cortex are important for information selection (BA 45/46).

Original languageEnglish (US)
Pages (from-to)824-834
Number of pages11
JournalNeuroImage
Volume27
Issue number4
DOIs
StatePublished - Oct 1 2005

Keywords

  • Episodic memory retrieval
  • Event-related fMRI
  • Neuroimaging
  • Precuneus
  • Prefrontal cortex
  • Source memory

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

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