The role of jet eccentricity in generating disproportionately elevated transaortic pressure gradients in patients with aortic stenosis

Amr E. Abbas, Laura M. Franey, Steven Lester, Gilbert Raff, Michael J. Gallagher, George Hanzel, Robert D. Safian, Philippe Pibarot

Research output: Contribution to journalArticle

9 Scopus citations


In patients with aortic stenosis (AS) and eccentric transaortic flow, greater pressure loss occurs as the jet collides with the aortic wall together with delayed and diminished pressure recovery. This leads to the elevated transaortic valve pressure gradients noted on both Doppler and cardiac catheterization. Such situations may present a diagnostic dilemma where traditional measures of stenosis severity indicate severe AS, while imaging modalities of the aortic valve geometric aortic valve area (GOA) suggest less than severe stenosis. In this study, we present a series of cases exemplifying this clinical dilemma and demonstrate how color M-mode, 2D and 3D transthoracic (TTE) and transesophageal (TEE) echocardiography, cardiac computed tomography angiography (CTA), and magnetic resonance imaging (MRI), may be used to resolve such discrepancies.

Original languageEnglish (US)
Pages (from-to)372-382
Number of pages11
Issue number2
StatePublished - Feb 1 2015



  • aortic valve stenosis
  • echocardiography
  • jet eccentricity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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