The role of eosinophils in rhinologic diseases

Jens Ponikau, Hirohito Kita, David A. Sherris

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The eosinophil granulocyte, although likely first observed by Wharton Jones in 1846 in unstained preparations of peripheral blood, was so named by Paul Ehrlich in 1879 because of the intense staining of its granules with the acidic dye eosin Gleich and Adolphson (Adv Immunol 39:177-253, 1986). Since that time, the eosinophil has been the subject of extensive investigation. Its occurrence in such disparate conditions as parasitic infections, presumably for the benefit of the human host, and hypersensitivity diseases, perhaps to the detriment of the patient, although paradoxical, has become better understood as a consequence of newer information. Eosinophils are resident and nonpathologic in various organs such as gastrointestinal tract and mammary glands, and they may play roles in tissue and immune homeostasis of these organs.

Original languageEnglish (US)
Title of host publicationNasal Physiology and Pathophysiology of Nasal Disorders
PublisherSpringer-Verlag Berlin Heidelberg
Pages95-108
Number of pages14
Volume9783642372506
ISBN (Print)9783642372506, 364237249X, 9783642372490
DOIs
StatePublished - Nov 1 2013

Fingerprint

Eosinophils
Parasitic Diseases
Human Mammary Glands
Eosine Yellowish-(YS)
Granulocytes
Gastrointestinal Tract
Hypersensitivity
Homeostasis
Coloring Agents
Staining and Labeling

Keywords

  • Chronic Rhinosinusits
  • Eosinophil
  • Innate and Acquired Immunity
  • Major Basic Protein (MBP)
  • Sinusitis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ponikau, J., Kita, H., & Sherris, D. A. (2013). The role of eosinophils in rhinologic diseases. In Nasal Physiology and Pathophysiology of Nasal Disorders (Vol. 9783642372506, pp. 95-108). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-37250-6_8

The role of eosinophils in rhinologic diseases. / Ponikau, Jens; Kita, Hirohito; Sherris, David A.

Nasal Physiology and Pathophysiology of Nasal Disorders. Vol. 9783642372506 Springer-Verlag Berlin Heidelberg, 2013. p. 95-108.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ponikau, J, Kita, H & Sherris, DA 2013, The role of eosinophils in rhinologic diseases. in Nasal Physiology and Pathophysiology of Nasal Disorders. vol. 9783642372506, Springer-Verlag Berlin Heidelberg, pp. 95-108. https://doi.org/10.1007/978-3-642-37250-6_8
Ponikau J, Kita H, Sherris DA. The role of eosinophils in rhinologic diseases. In Nasal Physiology and Pathophysiology of Nasal Disorders. Vol. 9783642372506. Springer-Verlag Berlin Heidelberg. 2013. p. 95-108 https://doi.org/10.1007/978-3-642-37250-6_8
Ponikau, Jens ; Kita, Hirohito ; Sherris, David A. / The role of eosinophils in rhinologic diseases. Nasal Physiology and Pathophysiology of Nasal Disorders. Vol. 9783642372506 Springer-Verlag Berlin Heidelberg, 2013. pp. 95-108
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