Abstract
Bilateral inferior petrosal sinus sampling is the gold standard diagnostic assay in identifying the pituitary source of adrenocorticotropic hormone secretion in Cushing syndrome. The noninvasive assays used in the workup of Cushing syndrome are often misleading or ambiguous, yielding sensitivities of up to only 80%. Inferior petrosal sinus sampling, however, is highly accurate and safe when performed in experienced centers. We review here the historical and technical details of the procedure, with emphasis on the relevant anatomy and a discussion of possible rare complications.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 132-138 |
| Number of pages | 7 |
| Journal | Diagnostic and Interventional Radiology |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2012 |
Keywords
- ACTH-secreting pituitary adenoma
- Cushing syndrome
- Inferior petrosal sinus sampling
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine
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Deipolyi, A., Karaosmanoǧlu, A., Habito, C., Brannan, S., Wicky, S., Hirsch, J., & Oklu, R. (2012). The role of bilateral inferior petrosal sinus sampling in the diagnostic evaluation of Cushing syndrome. Diagnostic and Interventional Radiology, 18(1), 132-138. https://doi.org/10.4261/1305-3825.DIR.4279-11.0