The role of bilateral inferior petrosal sinus sampling in the diagnostic evaluation of Cushing syndrome

Amy Deipolyi, Ali Karaosmanoǧlu, Cicero Habito, Scott Brannan, Stephan Wicky, Joshua Hirsch, Rahmi Oklu

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

Bilateral inferior petrosal sinus sampling is the gold standard diagnostic assay in identifying the pituitary source of adrenocorticotropic hormone secretion in Cushing syndrome. The noninvasive assays used in the workup of Cushing syndrome are often misleading or ambiguous, yielding sensitivities of up to only 80%. Inferior petrosal sinus sampling, however, is highly accurate and safe when performed in experienced centers. We review here the historical and technical details of the procedure, with emphasis on the relevant anatomy and a discussion of possible rare complications.

Original languageEnglish (US)
Pages (from-to)132-138
Number of pages7
JournalDiagnostic and Interventional Radiology
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2012

Keywords

  • ACTH-secreting pituitary adenoma
  • Cushing syndrome
  • Inferior petrosal sinus sampling

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'The role of bilateral inferior petrosal sinus sampling in the diagnostic evaluation of Cushing syndrome'. Together they form a unique fingerprint.

  • Cite this