TY - JOUR
T1 - The Relationship of Blood Cadmium Level to Hypertension and Plasma Norepinephrine Level
T2 - A Romanian Study (41159)
AU - Revis, N. W.
AU - Zinsmeister, A. R.
N1 - Funding Information:
Research sponsored by the Office of Health and Environmental Research, U.S. Department of Energy, under Contract W-7405-eng-26 with the Union Carbide Corp.
PY - 1981/6
Y1 - 1981/6
N2 - The associations of blood cadmium levels with hypertension and plasma norepinephrine concentrations were determined in normotensive and hypertensive nonsmokers and smokers. Statistical analysis showed that after adjustment for age alone, the estimated mean values of blood cadmium and plasma norepinephrine in nonsmokers were significantly (P < 0.001) lower than in smokers. However, after adjustment for age and blood cadmium, the estimated mean values for plasma norepinephrine were not significantly different between nonsmokers and smokers or normotensives and hypertensives. In contrast the estimated mean value for blood cadmium as a function of blood pressure (i.e., normotensive versus hypertensive) and smoking habit was still significant after adjustment for age and plasma norepinephrine (P < 0.01). We suggest that smoking and blood pressure affect the level of blood cadmium, and through this change in blood cadmium the level of plasma norepinephrine is affected.
AB - The associations of blood cadmium levels with hypertension and plasma norepinephrine concentrations were determined in normotensive and hypertensive nonsmokers and smokers. Statistical analysis showed that after adjustment for age alone, the estimated mean values of blood cadmium and plasma norepinephrine in nonsmokers were significantly (P < 0.001) lower than in smokers. However, after adjustment for age and blood cadmium, the estimated mean values for plasma norepinephrine were not significantly different between nonsmokers and smokers or normotensives and hypertensives. In contrast the estimated mean value for blood cadmium as a function of blood pressure (i.e., normotensive versus hypertensive) and smoking habit was still significant after adjustment for age and plasma norepinephrine (P < 0.01). We suggest that smoking and blood pressure affect the level of blood cadmium, and through this change in blood cadmium the level of plasma norepinephrine is affected.
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U2 - 10.3181/00379727-167-41159
DO - 10.3181/00379727-167-41159
M3 - Article
C2 - 7232432
AN - SCOPUS:0019513961
SN - 1535-3702
VL - 167
SP - 254
EP - 260
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
IS - 2
ER -