The quest for cortisone

Research output: Book/ReportBook

6 Scopus citations

Abstract

In 1948, when "Mrs. G.," hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound - cortisone - her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought "magic bullet" came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone's development, and looks at drugs that owe their heritage to the so-called "King of Steroids."

Original languageEnglish (US)
PublisherMichigan State University Press
Number of pages276
Volume9781609173265
ISBN (Electronic)9781609173265
ISBN (Print)9781611860337
StatePublished - 2012

ASJC Scopus subject areas

  • Arts and Humanities(all)

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  • Cite this

    Rooke, T. W. (2012). The quest for cortisone. Michigan State University Press.