Abstract
Bipolar disorder (BD) adversely affects daily activities/functioning. The Sheehan Disability Scale (SDS) assesses disability in work/school activities, family relationships, and social functioning, and it evaluates the functional impact of psychiatric disorders. BD outpatients from 21 U.S. sites completed a battery of validated instruments (including the SDS) three times over 8-12 weeks. Instrument reliability (internal consistency, test-retest), validity (construct, convergent validity, known groups) and responsiveness were measured. There were missing data for the SDS in 2% of the 225 subjects with BD. One factor explained 82% of the variance. All SDS items had rotated factor loadings on the first factor > 0.90, confirming the appropriateness of the SDS total score. Item-scale correlations surpassed 0.40. There was excellent internal consistency reliability for the SDS total score (Cronbach's alpha = 0.89). Test-retest reliability was acceptable for the SDS total score (intraclass correlation coefficient = 0.73). Correlations with other instruments demonstrate convergent and divergent validity. The SDS total and item scores significantly discriminated between (self-rated) overall health status, clinician-rated functional status, and clinician-rated depression, evidencing known group validity. The SDS demonstrated ability to detect change over time. The SDS is a valid, reliable measure of disability and is responsive to change over time when used in subjects with BD.
Original language | English (US) |
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Pages (from-to) | 163-174 |
Number of pages | 12 |
Journal | Psychiatry Research |
Volume | 165 |
Issue number | 1-2 |
DOIs | |
State | Published - Jan 30 2009 |
Keywords
- Bipolar disorder
- Disability
- Functioning
- Patient-reported outcome
- Sheehan Disability Scale
- Validation
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry