The "pseudo-CSF" signal of orbital optic glioma on magnetic resonance imaging: A signature of neurofibromatosis

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A five-and-a-half-year-old boy with neurofibromatosis had bilateral orbital optic gliomas visible on magnetic resonance imaging. Both tumors displayed a double-intensity signal characterized by a circumferential area of CSF-intensity tissue surrounding and sharply delimited from a central linear core of opposite signal intensity. The peripheral CSF-intensity signal in orbital optic glioma correlates with the histopathological finding of perineural arachnoidal gliomatosis and serves as a neuroradiologic marker for neurofibromatosis.

Original languageEnglish (US)
Pages (from-to)213-218
Number of pages6
JournalSurvey of ophthalmology
Issue number2
StatePublished - Jan 1 1993



  • magnetic resonance imaging
  • neurofibromatosis
  • optic nerve glioma
  • perineural arachnoidal gliomatosis

ASJC Scopus subject areas

  • Ophthalmology

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