TY - JOUR
T1 - The Physiology and Pathophysiology of Vitamin D
AU - AUDRAN, MAURICE
AU - KUMAR, RAJIV
PY - 1985
Y1 - 1985
N2 - The vitamin D endocrine system plays an important role in the maintenance of normal calcium homeostasis. Abnormalities of this system occur in many conditions, such as rickets, osteomalacia, hypoparathyroidism, and hyperparathyroidism. The diagnosis and treatment of these disorders will be facilitated if the clinician understands the general mechanisms by which defects in vitamin D metabolism and action occur. We review this information and discuss the use and limitations of vitamin D metabolite assays for diagnosis of clinical disorders of mineral metabolism.
AB - The vitamin D endocrine system plays an important role in the maintenance of normal calcium homeostasis. Abnormalities of this system occur in many conditions, such as rickets, osteomalacia, hypoparathyroidism, and hyperparathyroidism. The diagnosis and treatment of these disorders will be facilitated if the clinician understands the general mechanisms by which defects in vitamin D metabolism and action occur. We review this information and discuss the use and limitations of vitamin D metabolite assays for diagnosis of clinical disorders of mineral metabolism.
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U2 - 10.1016/S0025-6196(12)64791-0
DO - 10.1016/S0025-6196(12)64791-0
M3 - Review article
C2 - 3906291
AN - SCOPUS:0022389172
SN - 0025-6196
VL - 60
SP - 851
EP - 866
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 12
ER -