The noninvasive assessment of left ventricular diastolic function with two-dimensional and doppler echocardiography

Jae Kuen Oh, Christopher P. Appleton, Liv K. Hatle, Rick A. Nishimura, James B. Seward, A. Jamil Tajik

Research output: Contribution to journalArticle

520 Citations (Scopus)

Abstract

Left ventricular diastolic filling can be determined reliably by Doppler-derived mitral and pulmonary venous flow velocities. Diastolic filling abnormalities are broadly classified at their extremes to impaired relaxation and restrictive physiology with many patterns in between. An impaired relaxation pattern identifies patients with early stages of heart disease, and appropriate therapy may avert progression and functional disability. Pseudonormalization is a transitional phase between abnormal relaxation and restrictive physiology and signifies increased filling pressure and decreased compliance. In this phase, reducing preload, optimizing afterload, and treating the underlying disease are clinically helpful. A restrictive physiology pattern identifies advanced, usually symptomatic disease with a poor prognosis. Therapeutic intervention is directed toward normalizing loading conditions and improving the restrictive filling pattern, although this may not be feasible in certain heart diseases. Finally, many patients have left ventricular filling patterns that appear indeterminate or mixed. In these cases, clinical information, left atrial and left ventricular size, pulmonary venous flow velocity, and alteration of preload help assess diastolic function and estimate diastolic filling pressures.

Original languageEnglish (US)
Pages (from-to)246-270
Number of pages25
JournalJournal of the American Society of Echocardiography
Volume10
Issue number3
StatePublished - 1997

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Doppler Echocardiography
Left Ventricular Function
Heart Diseases
Lung
Compliance
Blood Pressure
Pressure
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

The noninvasive assessment of left ventricular diastolic function with two-dimensional and doppler echocardiography. / Oh, Jae Kuen; Appleton, Christopher P.; Hatle, Liv K.; Nishimura, Rick A.; Seward, James B.; Tajik, A. Jamil.

In: Journal of the American Society of Echocardiography, Vol. 10, No. 3, 1997, p. 246-270.

Research output: Contribution to journalArticle

Oh, Jae Kuen ; Appleton, Christopher P. ; Hatle, Liv K. ; Nishimura, Rick A. ; Seward, James B. ; Tajik, A. Jamil. / The noninvasive assessment of left ventricular diastolic function with two-dimensional and doppler echocardiography. In: Journal of the American Society of Echocardiography. 1997 ; Vol. 10, No. 3. pp. 246-270.
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