The natural history of lumbosacral plexopathy in cancer

K. A. Jaeckle, D. F. Young, K. M. Foley

Research output: Contribution to journalArticle

144 Citations (Scopus)

Abstract

We studied 85 cancer patients with lumbosacral plexopathy and documented pelvic tumor by CT orbiopsy. Three clinical syndromes were delineated: lower (L4-S1), 51%; upper (L1-L4), 31%; and pan-plexopathy (L1-S3), 18%. Seventy percent of patients had the insidious onset of pelvic or radicular leg pain, followed weeks to months later by sensory symptoms and weakness. The quintet of leg pain, weakness, edema, rectal mass, and hydronephrosis suggests plexopathy due to cancer. CT showed pelvic tumor in 96%. On myelography, epidural extension, usually below the conus medullaris, was seen in 45%. With treatment, only 28% of patients had objective responses on CT and 17% on examination.

Original languageEnglish (US)
Pages (from-to)8-15
Number of pages8
JournalNeurology
Volume35
Issue number1
StatePublished - 1985
Externally publishedYes

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Natural History
Neoplasms
Leg
Pain
Myelography
Hydronephrosis
Edema
Spinal Cord
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Jaeckle, K. A., Young, D. F., & Foley, K. M. (1985). The natural history of lumbosacral plexopathy in cancer. Neurology, 35(1), 8-15.

The natural history of lumbosacral plexopathy in cancer. / Jaeckle, K. A.; Young, D. F.; Foley, K. M.

In: Neurology, Vol. 35, No. 1, 1985, p. 8-15.

Research output: Contribution to journalArticle

Jaeckle, KA, Young, DF & Foley, KM 1985, 'The natural history of lumbosacral plexopathy in cancer', Neurology, vol. 35, no. 1, pp. 8-15.
Jaeckle KA, Young DF, Foley KM. The natural history of lumbosacral plexopathy in cancer. Neurology. 1985;35(1):8-15.
Jaeckle, K. A. ; Young, D. F. ; Foley, K. M. / The natural history of lumbosacral plexopathy in cancer. In: Neurology. 1985 ; Vol. 35, No. 1. pp. 8-15.
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